Recent Progress of Influenza Vaccine Production

Haochen Yu

2025

Abstract

In today's world of relatively complete public health, people still struggle with flu epidemics. Influenza vaccine is a good means of protection against influenza. However, there are still some shortcomings in today's influenza vaccine production technology. This paper focuses on influenza vaccine production. It first introduces the characteristics of influenza virus and the importance of vaccination. Then it summarizes two common production methods: the traditional chicken embryo preparation and cell substrate culture taking Madin-Darby Canine Kidney Cells (MDCK) cells as an example). The chicken embryo method has a long history, but is limited by low production efficiency and potential antigenicity changes. MDCK cell-based production has advantages like cell receptors similar to human cells, yet faces challenges such as poor cell growth and safety concerns. By comparing these methods, the study aims to identify existing problems. The outlook suggests further research on mammalian cell cultivation and gene--editing to improve vaccine production, with the ultimate goal of combining big data and artificial intelligence (AI) to predict virus mutations and enhance vaccine efficiency.

Paper Citation

in Harvard Style

Yu H. (2025). Recent Progress of Influenza Vaccine Production. In Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS; ISBN 978-989-758-789-4, SciTePress, pages 192-197. DOI: 10.5220/0014446200004933

in Bibtex Style

@conference{befs25,
author={Haochen Yu},
title={Recent Progress of Influenza Vaccine Production},
booktitle={Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS},
year={2025},
pages={192-197},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0014446200004933},
isbn={978-989-758-789-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS
TI - Recent Progress of Influenza Vaccine Production
SN - 978-989-758-789-4
AU - Yu H.
PY - 2025
SP - 192
EP - 197
DO - 10.5220/0014446200004933
PB - SciTePress