Design and Manufacturing of Microtextured Patient-Specific Coronary Stent

Francisco Franco-Martínez, William Solórzano-Requejo, William Solórzano-Requejo, Alejandro de Blas-de Miguel, Matthias Vostatek, Christian Grasl, Christian Grasl, Marta Bonora, Francesco Moscato, Francesco Moscato, Francesco Moscato, Andrés Díaz Lantada

2023

Abstract

Currently, the most usual treatment for coronary artery disease is the use of stents, which are produced with standard dimensions and shapes and the surgeon selects the one that best fits the patient’s anatomy. Due to this treatment, likelihood of restenosis might reach 40%. Additionally, thrombi formation is an important risk for these patients that is treated with anticoagulant medicines. Therefore, a design and manufacturing method to produce microtextured patient-specific coronary stent is developed with the aim to minimize the likelihood of restenosis and thrombosis. Stents consisting of unit cells structures that are regularly repeated to form a ring and, sometimes connectors to join the rings. To improve the fitting between artery and stent, parametric design of unit cell as a function of the length and mean radius of coronary artery is required. Then, the unit cell is microtextured to improve hemocompatibility using a bioinspired design in shark skin, which provide superhydrophobicity, drag reduction and oleophobicity under water conditions. Once the unit cell is micropatterned, a reverse engineering reconstruction is done to obtain the stent model. Finally, the design is manufactured with a 3D printer using two-photon polymerisation technology. SEM is used to evaluate the design and manufacturing method.

Paper Citation

in Harvard Style

Franco-Martínez F., Solórzano-Requejo W., de Blas-de Miguel A., Vostatek M., Grasl C., Bonora M., Moscato F. and Díaz Lantada A. (2023). Design and Manufacturing of Microtextured Patient-Specific Coronary Stent. In Proceedings of the 16th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2023) - Volume 1: BIODEVICES; ISBN 978-989-758-631-6, SciTePress, pages 142-149. DOI: 10.5220/0011691600003414

in Bibtex Style

@conference{biodevices23,
author={Francisco Franco-Martínez and William Solórzano-Requejo and Alejandro de Blas-de Miguel and Matthias Vostatek and Christian Grasl and Marta Bonora and Francesco Moscato and Andrés Díaz Lantada},
title={Design and Manufacturing of Microtextured Patient-Specific Coronary Stent},
booktitle={Proceedings of the 16th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2023) - Volume 1: BIODEVICES},
year={2023},
pages={142-149},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011691600003414},
isbn={978-989-758-631-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 16th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2023) - Volume 1: BIODEVICES
TI - Design and Manufacturing of Microtextured Patient-Specific Coronary Stent
SN - 978-989-758-631-6
AU - Franco-Martínez F.
AU - Solórzano-Requejo W.
AU - de Blas-de Miguel A.
AU - Vostatek M.
AU - Grasl C.
AU - Bonora M.
AU - Moscato F.
AU - Díaz Lantada A.
PY - 2023
SP - 142
EP - 149
DO - 10.5220/0011691600003414
PB - SciTePress