Photoluminescent Imaging for an Effective Cancer Diagnosis using Upconversion Nanoparticles

Rafia Rafique, Tae Park

Abstract

Advancements in the synthesis of upconversion nanoparticles (UCNP) can enable a broad range of biomedical applications. Herein, we fabricated NaYF4:Yb3+/Er3+ UCNP and polyacrylic acid conjugated UCNPs (UCNP@PAA). Characterizations of the resulting particles were conducted using electron microscopy and spectroscopy, X-ray diffraction (XRD), and upconversion luminescence (UCL) analysis. We demonstrated that particles were synthesized with good homogeneity, hexagonal phase, and UCL efficiency. The UCNP@PAA maintained their original particle size and luminescence properties, cellular nontoxicity, in vitro bioimaging, and biocompatibility. Based on these results, we suggest that these particles can be applied in drug-delivery systems and as bioimaging agents in the future.

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Paper Citation


in Harvard Style

Rafique R. and Park T. (2020). Photoluminescent Imaging for an Effective Cancer Diagnosis using Upconversion Nanoparticles.In Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 2: BIOIMAGING, ISBN 978-989-758-398-8, pages 23-27. DOI: 10.5220/0008691800230027


in Bibtex Style

@conference{bioimaging20,
author={Rafia Rafique and Tae Park},
title={Photoluminescent Imaging for an Effective Cancer Diagnosis using Upconversion Nanoparticles},
booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 2: BIOIMAGING,},
year={2020},
pages={23-27},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008691800230027},
isbn={978-989-758-398-8},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 2: BIOIMAGING,
TI - Photoluminescent Imaging for an Effective Cancer Diagnosis using Upconversion Nanoparticles
SN - 978-989-758-398-8
AU - Rafique R.
AU - Park T.
PY - 2020
SP - 23
EP - 27
DO - 10.5220/0008691800230027