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Authors: Woo-Chan Kim and Dong-Ho Cho

Affiliation: Korea Advanced Institute of Science and Technology, Korea, Republic of

Keyword(s): Repetitive Element, Tandem Repeat, Multiple Tandem Repeat Array, Systematic Analysis, Human Genome.

Related Ontology Subjects/Areas/Topics: Algorithms and Software Tools ; Bioinformatics ; Biomedical Engineering ; Model Design and Evaluation ; Sequence Analysis ; Structural Bioinformatics ; Structure Prediction

Abstract: Repetitive elements constitute the vast majority of the human genome and form many complex but highly-ordered patterns. Tandem repeats whose repeat units are placed next to each other particularly form very highly structured patterns in the human genome when homologous multiple tandem repeats are close together. In this paper, the structure of the multiple tandem repeat array (MTRA) is analyzed based on systematic analysis. The proposed system for analyzing MTRA derives the original tandem repeat units by using the characteristics of homology of MTRA and represents diagram model to show the structure of MTRA easily. The analysis results of the four MTRAs in the human genome are shown and the proposed algorithm is proved to be very efficient for analyzing MTRA by the comparison of three conventional algorithms.

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Paper citation in several formats:
Kim, W. and Cho, D. (2013). Systematic Analysis of Structure of Multiple Tandem Repeat Arrays in the Human Genome. In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2013) - BIOINFORMATICS; ISBN 978-989-8565-35-8; ISSN 2184-4305, SciTePress, pages 44-52. DOI: 10.5220/0004243300440052

@conference{bioinformatics13,
author={Woo{-}Chan Kim. and Dong{-}Ho Cho.},
title={Systematic Analysis of Structure of Multiple Tandem Repeat Arrays in the Human Genome},
booktitle={Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2013) - BIOINFORMATICS},
year={2013},
pages={44-52},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004243300440052},
isbn={978-989-8565-35-8},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2013) - BIOINFORMATICS
TI - Systematic Analysis of Structure of Multiple Tandem Repeat Arrays in the Human Genome
SN - 978-989-8565-35-8
IS - 2184-4305
AU - Kim, W.
AU - Cho, D.
PY - 2013
SP - 44
EP - 52
DO - 10.5220/0004243300440052
PB - SciTePress

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