Preventive Strategies for Soft Tissue Injuries of the Ankle
Yanfu Li
College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, 350122, Fuzhou, Fujian, China
Keywords: Ankle Soft Tissue Injuries, Prevention Strategies, Chronic Ankle Instability.
Abstract: Soft tissue injury of the ankle joint is a condition that has an acute onset and is prone to recurrence. According
to relevant statistical data, chronic instability of the ankle joint is the most common complication, severely
affecting quality of life and reducing life experience. This article summarizes previous research evidence,
synthesizes relevant guidelines, and analyzes expert consensus to extract effective measures to reduce the
incidence of soft tissue injuries of the ankle joint and decrease recurrences. Based on existing data, it is found
that the treatment involves multiple stages and various treatment methods. Therefore, this article integrates
and summarizes different treatment strategies for different populations and stages of ankle joint soft tissue
injuries, presenting them in the form of a three-level prevention strategy, aiming to provide procedural
references for the treatment and prognosis of ankle joint soft tissue injuries and further promote the
standardization of prevention and treatment.
1 INTRODUCTION
Soft tissue injuries of the ankle, particularly lateral
ankle ligament injuries, are among the most common
musculoskeletal injuries. They account for
approximately 10% of all emergency department
visits and 30% of all sports-related injuries
(Swiontkowski, M.F.,2004). Individuals engaged in
activities such as jumping, running, and rapid
direction changes face a higher risk. Among 200
high-level competitive aerobics athletes from China,
ankle injuries accounted for about 45% of all risks
(Ma,X. ,2024).Additionally, a gender difference has
been observed, with female athletes being
approximately 25% more likely to sustain soft tissue
injuries to the ankle compared to male athletes (Marín
Fermín, T., 2023).The increasing popularity of ball
sports has further contributed to the rise in the
incidence of these injuries, significantly impacting
patients' daily lives and imposing substantial medical
costs for initial and follow-up treatments.
Although soft tissue injuries of the ankle joint
have a high incidence in various populations, the
treatment methods following such injuries are still
under discussion. While rehabilitation is the
cornerstone of conservative treatment, the extent and
severity of the injury are often not clearly defined at
the time of diagnosis, leading to poor timeliness in the
formulation and implementation of rehabilitation
strategies. This may result in adverse outcomes,
including high recurrence rates, persistent symptoms,
reduced levels of physical activity, functional
impairment, and decreased quality of life. Research
indicates that approximately 70% of patients with
initial ankle sprains will experience recurrence or
progress to chronic ankle instability and osteoarthritis
(Marín Fermín, T., 2023). However, the
epidemiology of chronic ankle instability remains
unknown, and the long-term outcomes of post-
traumatic osteoarthritis are poor; therefore,
preventing soft tissue injuries to the ankle is crucial.
By adopting a three-tiered prevention approach to
prevent the occurrence, progression, and recurrence
of ankle injuries, primary prevention targets
individuals whose ankles have not yet been injured;
secondary prevention focuses on patients in the acute
phase of injury; and tertiary prevention primarily
aims to prevent the recurrence and adverse sequelae
of ankle injuries. Tertiary prevention plays an
important role in improving the cure rate of soft tissue
injuries in the ankle, reducing incidence and
recurrence rates. At the same time, it effectively
optimizes resource utilization, ultimately lowering
the risk of re-injury and improving long-term
prognosis.
398
Li, Y.
Preventive Strategies for Soft Tissue Injuries of the Ankle.
DOI: 10.5220/0014494000004933
Paper published under CC license (CC BY-NC-ND 4.0)
In Proceedings of the 1st International Conference on Biomedical Engineering and Food Science (BEFS 2025), pages 398-402
ISBN: 978-989-758-789-4
Proceedings Copyright © 2026 by SCITEPRESS Science and Technology Publications, Lda.
2 PRIMARY PREVENTION
The causative factors for soft tissue injuries of the
ankle are varied, and a large body of literature points
to the development of injuries in relation to self-
associated internal risk factors as well as many
potential external risk factors. The aim of primary
prevention is to modify the external environment and
internal risks in order to effectively avoid them and to
improve one's own fitness, thereby reducing the risk
of first-time injuries in the healthy population.
2.1 Risk Factors in the External
Environment and the Prevention
In addition to occurring during exercise, soft tissue
injuries to the ankle are also prone to occur on
slippery or uneven surfaces and can even be
dangerous due to oversized shoes or insufficient
upper support. For older adults, the risk is also higher
in dimly lit scenes and when walking up and down
stairs. In private environments, environmental
modifications can be made with the knowledge of a
rehabilitation professional, such as increasing the
brightness of the environment, reducing floor clutter,
and preventing slippery floors. In public places, the
risk rate can be reduced by wearing non-slip shoes
with hard uppers, paying attention to uneven slippery
surfaces underfoot, and carrying crutches for the
elderly.
2.2 Internal Risk Factors and Their
Prevention
2.2.1 Body Mass Index (BMI)
Research has indicated a substantial correlation
between ankle soft tissue injuries and body mass
index. Ankle soft tissue injuries are generally more
likely to occur in those with a higher body mass
index. Ankle and foot soft tissue injuries had a
significant association with higher BMI, according to
the results of Mendelian randomized analysis
investigating the causal relationship between BMI
and joint injuries (Bi, W., 2023). Therefore, it may be
possible to lower the risk of ankle soft tissue injuries
by keeping body mass index within the population
mean range of 26.5-31.2 kg/m².
2.2.2 Muscle Strength
The difference in eccentric isometric strength of the
ankle flexors between sides is a risk factor for ankle
sprains.Specifically, soccer players with
asymmetrical centrifugal ankle strength had an 9-fold
increased risk of sprains due to ankle sprains. It has
been shown that increasing muscle strength in the
pyriformis muscle is effective in avoiding lateral
ankle ligament injuries, and training in all four
directions using elastic bands may also increase
muscle strength around the ankle joint, thereby
decreasing the risk of ankle soft tissue injuries (Ge,
Q., 2025).
2.2.3 Exercise Habits
Proper warm-up before exercise is usually effective
in avoiding the risk of soft tissue injuries in the ankle
joint. A study showed that among young athletes,
participants in balance training programs had
significantly fewer ankle injuries compared to the
control group (p < 0.05) ( Nováková, T.,
2021) .Therefore, by maintaining the muscles at an
appropriate temperature, enhancing muscle elasticity
and extensibility to levels suitable for exercise, and
promoting proprioceptive neuromuscular training and
control of body awareness and kinesthesia, In
addition to sufficient basic warm-up activities,
incorporating high-intensity exercises, such as sprints
and other explosive training, during the warm-up
period effectively prevents the occurrence of soft
tissue injuries in the ankle joint ( Pieters, D.,2022).
3 SECONDARY PREVENTION
Ankle soft tissue injury tends to occur suddenly and
to varying degrees, and the treatment methods used
vary with the different periods following the injury.
Attention should be paid to the treatment methods
used in the acute phase, which tend to have a greater
impact on the prognosis and the patient's satisfaction
with the treatment, as well as on the prognosis of the
short-term treatment and the recovery period.
3.1 Cold Therapy
Reports have shown that the use of ice in the acute
phase of ankle sprains provides better pain relief than
the use of analgesics. But cryotherapy is less effective
during the recovery phase after injury; therefore,
cryotherapy should only be used in the acute phase of
injury to alleviate pain and reduce swelling at the
injury site.
Preventive Strategies for Soft Tissue Injuries of the Ankle
399
3.2 External or Functional Support
Many studies have shown that after pain relief from
acute ankle soft tissue injuries, it is crucial to
immobilize the affected area using external or
functional support devices. This not only prevents
secondary injuries through the immobilization of the
relevant area but also protects it from further external
harm. Currently, commonly used bandages or
pressure fixation devices are employed for
emergency immobilization, and patients use
wheelchairs or crutches to prevent weight-bearing on
the injured area, which can reduce pain and promote
recovery.
3.3 Non-Viral Anti-Inflammatory
Drugs (NSAIDs)
NSAIDs have anti-inflammatory and analgesic
effects, and their use during the acute phase of soft
tissue injury in the ankle can effectively alleviate
patient discomfort, making them a recommended
treatment option. However, long-term use can
significantly increase the likelihood of complications
such as renal dysfunction and nonunion of bones.
Therefore, it is advised to use NSAIDs only for a
short term during the acute postoperative phase.
3.4 Manual Therapy
The application of physical therapy can effectively
improve treatment outcomes in the acute phase. It can
flexibly adjust techniques and intervention levels
based on different injury conditions, demonstrating
strong adaptability. Furthermore, based on scientific
analysis and relevant treatment methods, it can reduce
patients' rehabilitation time and enhance
rehabilitation efficiency. In addition, improvements
in various assessment scales now enable physical
therapists to provide timely treatment after patients'
soft tissue injuries to the ankle joint.
4 TERTIARY PREVENTION
Tertiary prevention can play an important role in
reducing recurrence rates and complications by
aggressively treating common symptoms after ankle
soft tissue injuries. Studies have pointed out that the
most common complication after initial ankle soft
tissue injury is chronic ankle joint instability (CAJ),
which is why most people are prone to re-injury after
initial ankle injury. Therefore, systematic
rehabilitation and prognostic protection play an
important role in preventing re-injury to the soft
tissues of the ankle.
4.1 Systematic Rehabilitation Training
4.1.1 Strengthening of Muscle
Improvement of muscle strength is recognized as an
important means of enhancing joint stability and
preventing re-injury to the soft tissues of the ankle.
Muscle strength building has been used in a variety of
rehabilitation methods for ankle injuries and is
considered a primary measure in the early stages of
injury. In an analysis of 200 aerobic athletes, it was
found that the incidence of ankle injuries was
inversely related to the level of exercise, and that for
professional athletes, the differences in physical
fitness were greater than the differences in skill, with
which muscular strength is usually associated. After
the control group was treated with acoustic waves
while the experimental group was treated by
strengthening the muscles around the ankle joint, it
was found that the total effective rate of treatment in
the experimental group was higher than that of the
control group (p < 0.05) (Li, X.,2022).And it was not
easy to recur, so it can be concluded that the
strengthening of the muscles in the relevant areas can
effectively prevent the occurrence of soft tissue
injuries of the ankle joint.
4.1.2 Enhanced Proprioception
The control of proprioception is closely related to
neuromuscular, for the enhancement of
proprioception training is often not the only way,
mainly through the enhancement of neuromuscular
regulation of integration, so that the individual for
their own postural judgment, the perception of
movement and the activation of motor units more
agile. The cause of recurrent sprains is also related to
impaired proprioceptors after the first injury to the
ankle ligaments. Therefore, strengthening
proprioception, primarily through balance training, is
also effective in reducing the risk of ankle soft tissue
injuries.
4.1.3 Conventional Intervention Plan
In a study involving 43 patients with CAI, a 4-week
intervention with resistance bands and a
biomechanical ankle platform system was conducted
three times a week. Using the foot lift test, balance
test, and 8-shaped jump test, it was found that each
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intervention group showed improvement compared to
the control group that did not engage in related
exercises (p < 0.05)(Cain, M. S., 2020).This was
primarily achieved through a set of 10 repetitions,
repeated 3 times, of ankle eversion, inversion,
dorsiflexion, and plantarflexion exercises using
resistance bands, and exercises on the biomechanical
ankle platform system that involved changing the
rotation direction clockwise or counterclockwise
every 10 seconds during a 40-second activity, which
can effectively improve CAI.
4.2 Sports Protection
Following an ankle injury, exercise is often
recommended to facilitate recovery and adaptation to
normal life. To prevent re-injury during exercise, a
systematic evaluation incorporating rue therapy has
shown that the use of a kinesio tape application to
assess kinesio tape (KT) is effective in improving
functional gait stability and ankle stability during
exercise. This effectively reduces the risk of ankle re-
injury (Liu, Q., 2024).
5 CONCLUSION
Primary prevention involves improving and
controlling external environmental risks, as well as
managing one's BMI, muscle strength, and exercise
habits to prevent soft tissue injuries of the ankle joint,
providing preventive measures for individuals with
uninjured ankles. In secondary prevention, cold
therapy or short-term use of NSAIDs is applied to
patients with acute ankle soft tissue injuries to
alleviate initial discomfort, while external functional
support and manual therapy are used to enhance
short-term treatment and provide support for
prognosis and recovery. For patients with
rehabilitated ankle soft tissue injuries, tertiary
prevention involves systematic rehabilitation training
and protective measures in physical activities to avoid
recurrence, while enhancing proprioception and
muscle strength through traditional interventions can
also improve ankle stability and effectively prevent
the occurrence of related complications.
In addition, long-term patient education and
adherence to maintenance plans play a crucial role in
maintaining ankle joint health. As research continues
to advance, the integration of innovative
rehabilitation techniques and personalized treatment
approaches will further improve tertiary prevention
strategies. The correlation between different risk
factors and incidence will also be analyzed more
accurately through scale analysis. With the
development of artificial intelligence, prevention
measures at all levels will also incorporate individual
differences for more detailed analysis and provide
prioritized treatment methods, offering guidance for
clinical and public treatment.
By prioritizing comprehensive rehabilitation,
external support measures, and long-term injury
management, clinicians and patients can work
together to reduce the burden of soft tissue injuries in
the ankle and improve overall functional outcomes.
At the same time, the current literature generally
suffers from issues such as small sample sizes,
significant age differences among samples, limited
discussion of gender differences, and non-
standardized rehabilitation methods at various levels.
Through technological breakthroughs and the
integration of multidimensional strategies, it is
possible to significantly reduce the incidence of
injuries, improve prognosis, and enhance the quality
of life for patients. Furthermore, progress in this field
relies not only on technological innovation but also
on the integration of social resources and the
enhancement of public health awareness. It is hoped
that more research outcomes will contribute to the
supplementation and improvement of this field in the
future.
REFERENCES
Bi, W., Yang, M., & Jiang, C. (2023). Causal effect of body
mass index and physical activity on the risk of joint
sports injuries: Mendelian randomization analysis in
the European population. Journal of orthopaedic
surgery and research, 18(1), 676.
Cain, M. S., Ban, R. J., Chen, Y. P., Geil, M. D., Goerger,
B. M., & Linens, S. W. (2020). Four-Week Ankle-
Rehabilitation Programs in Adolescent Athletes With
Chronic Ankle Instability. Journal of athletic training,
55(8), 801–810.
Ge, Q., Xu, D., Zhang, Z., Baker, J. S., & Zhou, H. (2025).
Exploring Lower Limb Biomechanical Differences in
Competitive Aerobics Athletes of Different Ability
Levels During Rotational Jump Landings.
Bioengineering (Basel, Switzerland), 12(3), 220.
Li, X., Kang,M.(2022). Athletes’ ankle injury features and
rehabilitation methods based on internet big data.
Journal of Nanomaterials.
Liu, Q., Wang, L., Dai, F., Wang, G., & Chen, P. (2024).
Effects of ankle Kinesio taping on knee and ankle joint
biomechanics during unanticipated jumps in collegiate
athletes. PloS one, 19(8), e0305480.
Preventive Strategies for Soft Tissue Injuries of the Ankle
401
Ma,X. (2024).The current situation of sport injuries among
high-level competitive aerobics athletes and the effect
of rehabilitation training on sports injuries. Journal of
Biotech Research. 18,132-139.
Marín Fermín, T., Al-Dolaymi, A. A., & D'Hooghe, P.
(2023). Acute Ankle Sprain in Elite Athletes: How to
Get Them Back to the Game?. Foot and ankle clinics,
28(2), 309–320.
Nováková, T., Tufano, J., Veseláková, A.(2021) 12 months
of balance training decreases ankle-joint injury
frequency in young girl basketball players. Acta
Facultatis Educationis Physicae Universitatis
Comenianae. 61(2):214-227.
Pieters, D., Wezenbeek, E., De Ridder, R., Witvrouw, E., &
Willems, T. (2022). Acute Effects of Warming Up on
Achilles Tendon Blood Flow and Stiffness. Journal of
strength and conditioning research, 36(10), 2717–2724.
Swiontkowski, M.F. (2004) Manual de Ortopedia y
traumatología. Elsevier España.2A ed.
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