Practical Characterization of Cell-Electrode Electrical Models in Bio-Impedance Assays

Juan A. Serrano, Pablo Pérez, Andrés Maldonado, María Martín, Alberto Olmo, Paula Daza, Gloria Huertas, Alberto Yúfera

Abstract

This paper presents the fitting process followed to adjust the parameters of the electrical model associated to a cell-electrode system in Electrical Cell-substrate Impedance Spectroscopy (ECIS) technique, to the experimental results from cell-culture assays. A new parameter matching procedure is proposed, under the basis of both, mismatching between electrodes and time-evolution observed in the system response, as consequence of electrode fabrication processes and electrochemical performance of electrode-solution interface, respectively. The obtained results agree with experimental performance, and enable the evaluation of the cell number in a culture, by using the electrical measurements observed at the oscillation parameters in the test circuits employed.

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Paper Citation


in Harvard Style

Serrano J., Pérez P., Maldonado A., Martín M., Olmo A., Daza P., Huertas G. and Yúfera A. (2018). Practical Characterization of Cell-Electrode Electrical Models in Bio-Impedance Assays.In Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, ISBN 978-989-758-277-6, pages 100-108. DOI: 10.5220/0006712601000108


in Bibtex Style

@conference{biodevices18,
author={Juan A. Serrano and Pablo Pérez and Andrés Maldonado and María Martín and Alberto Olmo and Paula Daza and Gloria Huertas and Alberto Yúfera},
title={Practical Characterization of Cell-Electrode Electrical Models in Bio-Impedance Assays},
booktitle={Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES,},
year={2018},
pages={100-108},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006712601000108},
isbn={978-989-758-277-6},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES,
TI - Practical Characterization of Cell-Electrode Electrical Models in Bio-Impedance Assays
SN - 978-989-758-277-6
AU - Serrano J.
AU - Pérez P.
AU - Maldonado A.
AU - Martín M.
AU - Olmo A.
AU - Daza P.
AU - Huertas G.
AU - Yúfera A.
PY - 2018
SP - 100
EP - 108
DO - 10.5220/0006712601000108