Innovations and Challenges in Influenza Vaccine Development and Global Deployment

Yujin Hao

2025

Abstract

Influenza remains a major global public health challenge, causing an estimated 290,000 to 650,000 respiratory-related deaths annually. Traditional egg-based vaccines are limited by slow production cycles and reduced efficacy due to antigenic drift. In contrast, mRNA and recombinant protein vaccines have improved production speed and immune response. mRNA vaccines offer up to 89.6% protection against H1N1, while recombinant vaccines have enhanced efficacy in older adults by 30%. Despite these advances, challenges such as high costs, cold-chain requirements, and low global vaccination coverage hinder effective control. This review highlights recent vaccine design innovations and evaluates ongoing issues, including viral evolution, immune durability, and access disparities.

Paper Citation

in Harvard Style

Hao Y. (2025). Innovations and Challenges in Influenza Vaccine Development and Global Deployment. In Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS; ISBN 978-989-758-789-4, SciTePress, pages 426-429. DOI: 10.5220/0014494500004933

in Bibtex Style

@conference{befs25,
author={Yujin Hao},
title={Innovations and Challenges in Influenza Vaccine Development and Global Deployment},
booktitle={Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS},
year={2025},
pages={426-429},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0014494500004933},
isbn={978-989-758-789-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS
TI - Innovations and Challenges in Influenza Vaccine Development and Global Deployment
SN - 978-989-758-789-4
AU - Hao Y.
PY - 2025
SP - 426
EP - 429
DO - 10.5220/0014494500004933
PB - SciTePress