A Promising Therapy in Cancer Treatment: CRISPR-Cas9 Gene Editing, Its Improvements, Combination Therapies, and Future Developments

Yuman Sui

2025

Abstract

Cancer, which was caused by uncontrollable cell growth, brings pain and despair to patients and their families. Individuals in the field of cancer biology never stop finding new therapies effective enough to save sufferers from huge torments. Crispr-Cas9 is characterized by its ability to cut off designated DNA segments. Consequently, scientists take advantage of it to silence the expression of certain genes suspectable in triggering the growth of tumor cells. This review is primarily going to focus on explaining what the CRISPR-Cas9 is, including the origin of CRISPR-Cas9 system and composition of it, and elaborate on its working mecha-nisms. Then the article will talk about clinical applications, such as CRISPR-Cas9’s role in co-lon cancer and Gallbladder cancer, and existing challenges from medical, ethical perspectives. Finally, it will introduce a combined therapy: CRISPR-Cas9 gene editing technology and CAR-T cell immunotherapy in the treatment of cancer and future development of gene therapy.

Paper Citation

in Harvard Style

Sui Y. (2025). A Promising Therapy in Cancer Treatment: CRISPR-Cas9 Gene Editing, Its Improvements, Combination Therapies, and Future Developments. In Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS; ISBN 978-989-758-789-4, SciTePress, pages 248-253. DOI: 10.5220/0014486000004933

in Bibtex Style

@conference{befs25,
author={Yuman Sui},
title={A Promising Therapy in Cancer Treatment: CRISPR-Cas9 Gene Editing, Its Improvements, Combination Therapies, and Future Developments},
booktitle={Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS},
year={2025},
pages={248-253},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0014486000004933},
isbn={978-989-758-789-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS
TI - A Promising Therapy in Cancer Treatment: CRISPR-Cas9 Gene Editing, Its Improvements, Combination Therapies, and Future Developments
SN - 978-989-758-789-4
AU - Sui Y.
PY - 2025
SP - 248
EP - 253
DO - 10.5220/0014486000004933
PB - SciTePress