Application and Development of Structural Vaccinology in Vaccine Molecular Design Steps

Haoyan Jiang

2025

Abstract

Structural vaccinology has a broad prospect, which takes genomic research as a basis, combines research directions from multiple disciplines, and advocates the use of surface proteins or three-dimensional structures of pathogens to guide vaccine design. However, there is still a lack of systematic knowledge about structural vaccinology's specific mechanism and application value in vaccine molecular design. This paper provides a brief introduction to structural vaccinology and the molecular design of vaccines, a review of the application of structural vaccinology in molecular design, an in-depth discussion of the role of structural vaccinology in the determination of antigenic epitopes, epitope synthesis and vector construction, and finally a brief overview of the current status and prospects of structural vaccinology. By collecting and analysing relevant data, this paper discusses in depth the application strategies, technological progress and future development direction of structural vaccinology in the key aspects of vaccine molecular design to provide new ideas and methodological references for vaccine research and development.

Paper Citation

in Harvard Style

Jiang H. (2025). Application and Development of Structural Vaccinology in Vaccine Molecular Design Steps. In Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS; ISBN 978-989-758-789-4, SciTePress, pages 198-202. DOI: 10.5220/0014446300004933

in Bibtex Style

@conference{befs25,
author={Haoyan Jiang},
title={Application and Development of Structural Vaccinology in Vaccine Molecular Design Steps},
booktitle={Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS},
year={2025},
pages={198-202},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0014446300004933},
isbn={978-989-758-789-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS
TI - Application and Development of Structural Vaccinology in Vaccine Molecular Design Steps
SN - 978-989-758-789-4
AU - Jiang H.
PY - 2025
SP - 198
EP - 202
DO - 10.5220/0014446300004933
PB - SciTePress