Research Progress on the Role of N6-Methyladenosine in the Development of Diabetes

Jingyi Huang

2025

Abstract

N6-methyladenosine (m6A) is a key RNA modification widely found in eukaryotic mRNA, regulating RNA stability, translation, splicing, and degradation. Recent studies highlight its critical role in diabetes development by modulating insulin signaling, islet β-cell function, immune response, and lipid metabolism. Additionally, m6A modification contributes to diabetic complications, such as retinopathy and nephropathy, by influencing gene expression. Advances in technology have led to the identification of numerous diabetes-related genes targeted by m6A, opening new therapeutic possibilities. Understanding the molecular mechanisms of m6A in different diabetes types may aid in precision medicine approaches. This review explores the potential of targeting m6A modification for early intervention and treatment, providing novel insights into diabetes management. Future research on m6A's role in diabetes pathogenesis and complications will enhance our ability to develop innovative therapeutic strategies, improving outcomes for diabetic patients.

Paper Citation

in Harvard Style

Huang J. (2025). Research Progress on the Role of N6-Methyladenosine in the Development of Diabetes. In Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS; ISBN 978-989-758-789-4, SciTePress, pages 180-186. DOI: 10.5220/0014440300004933

in Bibtex Style

@conference{befs25,
author={Jingyi Huang},
title={Research Progress on the Role of N6-Methyladenosine in the Development of Diabetes},
booktitle={Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS},
year={2025},
pages={180-186},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0014440300004933},
isbn={978-989-758-789-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS
TI - Research Progress on the Role of N6-Methyladenosine in the Development of Diabetes
SN - 978-989-758-789-4
AU - Huang J.
PY - 2025
SP - 180
EP - 186
DO - 10.5220/0014440300004933
PB - SciTePress