Phytochemicals in Alzheimer’s Prevention: Causes and Potentials

Yijia Li

2025

Abstract

Alzheimer’s disease is a prevalent neurodegenerative disorder around the world, characterized by amyloid-beta (Aβ) aggregation and tau hyperphosphorylation, affecting more than 55 million of people worldwide. The pathogenesis of Alzheimer’s disease is a complex issue, influenced by aging, air pollution, toxic metals, chronic diseases, and diet. While current treatments provide limited symptomatic relief, phytochemicals, including flavonoids, polyphenolic compounds, alkaloids, terpenes, and polysaccharides, particularly traditional Chinese herbs, have demonstrated their unique potential in AD prevention and therapy. These plant-based substances show potentials in mitigating oxidative stress, reducing neuroinflammation, and enhancing mitochondrial function. This review offers a detailed analysis of typical medicinal plants, especially rose flavonoids, and provides a comprehensive view of both the role of plant-based bioactive substances as a promising alternative in AD prevention and current challenges, like bioavailability and brain penetration. Despite these obstacles, innovative solutions are being explored to improve their therapeutic efficacy.

Paper Citation

in Harvard Style

Li Y. (2025). Phytochemicals in Alzheimer’s Prevention: Causes and Potentials. In Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS; ISBN 978-989-758-789-4, SciTePress, pages 90-99. DOI: 10.5220/0014401200004933

in Bibtex Style

@conference{befs25,
author={Yijia Li},
title={Phytochemicals in Alzheimer’s Prevention: Causes and Potentials},
booktitle={Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS},
year={2025},
pages={90-99},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0014401200004933},
isbn={978-989-758-789-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Biomedical Engineering and Food Science - Volume 1: BEFS
TI - Phytochemicals in Alzheimer’s Prevention: Causes and Potentials
SN - 978-989-758-789-4
AU - Li Y.
PY - 2025
SP - 90
EP - 99
DO - 10.5220/0014401200004933
PB - SciTePress