Synergy of H2O2 and Methionine Affects Tyrosinase Activity, Causing Repigmentation of Gray Hair

Haiming Sun

2022

Abstract

Hair colour demonstrates people’s health condition. The most prevalent explanation for hair graying is that peroxides oxidize tyrosinase, preventing this enzyme from activating melanocytes. From Schallreuter’s paper in 2004, hydrogen peroxide was found to activate acetylcholinesterase, the enzyme crucial in treatment of vitiligo. Vitiligo is supposed to be caused by deactivation of pigment cells, like the possible cause of hair graying. Meanwhile, methionine has long been considered to eliminate peroxides. Therefore, it’s attractive to see that if the combination of the two materials, hydrogen peroxide and methionine, will activate tyrosinase more largely than any one of them do. This research uses the rate of L-Dopachrome formation to determine tyrosinase activity. There are two possible results. The ideal result is the synergy of methionine and hydrogen peroxide activates tyrosinase. However, since hydrogen peroxide can deactivate tyrosinase, the two activations may cancel out so there is no significant change in tyrosinase activity. If synergy of hydrogen peroxide and methioine do activate tyrosinase better, then the problem of hair graying can be better solved.

Paper Citation

in Harvard Style

Sun H. (2022). Synergy of H2O2 and Methionine Affects Tyrosinase Activity, Causing Repigmentation of Gray Hair. In Proceedings of the 4th International Conference on Biotechnology and Biomedicine - Volume 1: ICBB; ISBN 978-989-758-637-8, SciTePress, pages 92-96. DOI: 10.5220/0012013800003633

in Bibtex Style

@conference{icbb22,
author={Haiming Sun},
title={Synergy of H2O2 and Methionine Affects Tyrosinase Activity, Causing Repigmentation of Gray Hair},
booktitle={Proceedings of the 4th International Conference on Biotechnology and Biomedicine - Volume 1: ICBB},
year={2022},
pages={92-96},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0012013800003633},
isbn={978-989-758-637-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biotechnology and Biomedicine - Volume 1: ICBB
TI - Synergy of H2O2 and Methionine Affects Tyrosinase Activity, Causing Repigmentation of Gray Hair
SN - 978-989-758-637-8
AU - Sun H.
PY - 2022
SP - 92
EP - 96
DO - 10.5220/0012013800003633
PB - SciTePress