the  need  for  a  "large"  amount  of  all  resources, 
inability  to  implement  all  the  innovations. 
Disadvantages - a high burden falls on the protection 
of  inventions  and  innovations  from  copying, 
including  patenting,  registration  of  designs,  and 
copyright  (Lambert  and  Franz,  2008).  The  second 
direction is the implementation of open innovations - 
innovations,  created by  the scientific community  or 
within  a  corporation,  but  “working”  outside  the 
organization. Advantages: the problem solution rate 
increases, the cost of development is lower, etc.) (No. 
18  of  the  criterion),  disadvantages  -  high  risks  of 
"information  leakage" and  loss of  professional  staff 
("recruiting")  (Sukhareva,  2021).  Recently,  an 
opinion  has  been  formed  that  “innovations  can  be 
implemented  as  a  result  of  the  integration  of 
knowledge, experience, the results of good analytics, 
socialization; “physical and digital platforms involve 
representatives  of  various  industries  and  scientific 
disciplines  in  co-production,  and  promote  “cross-
pollination”"  (Wise  et  al.,  2016).  That  is,  it  is 
important to maintain a “balance” of open and closed 
innovation. 
4. Lean production organization and activation of 
digitalization of innovation activities. The active and 
obsessive  digitalization  of  technology  based  on 
robotics, neurotechnology, artificial intelligence, the 
Internet, etc. The author Kostin identifies three main 
effects from the introduction of digital technologies: 
differentiation (based on targeted online advertising), 
formation  of  new  income  sources  of  income  (based 
on  online  sales  growth),  cost  reduction  (based  on 
"revenue"  management)  (Kostin,  2017).  Seemingly 
endless  opportunities  for  business  development 
appear  (although  we  already  talk  about  "digital 
fatigue").  But  the  organization  Disruptive  digital 
innovation  (DDI)  requires  costs  and  considerable 
costs (Darlington et al., 2021)  for example, in Russia 
alone,  “Digital  Region”  federal  project  included  in 
the “Digital Economy” program will require 247 bln. 
rubles over five years (Korolev, 2020): infrastructure, 
software,  communications,  personnel  training,  etc., 
“contradicting”  “lean  production”  principles 
(Thorbjörn, 2019). Sometimes a model of “lean start-
ups” is proposed, which implies increased flexibility 
and  a  reduction  in  the  innovation  process  duration 
(Wise  et  al.,  2016),  but  such  models  are  not 
numerous.  Therefore,  it  is  so  important  to  find  a 
"happy medium" for digitalization and rational use of 
resources. 
5.  Combinations  of  flexibility  and  rigidity  of 
integration forms of cooperation in the organization 
of innovation. The regional innovation potential, the 
search for a balance of open and closed, disruptive or 
gradual  innovations,  the  costs  of  digitalization  and 
lean  manufacturing,  we  assume  the  possibility  of 
forming integration structures in the region, both new 
rigid  organizational  forms  and  consortia. 
Implementation of certain innovations may require a 
"rigid"  management  structure,  for  others  -  only 
temporary  "creative"  project-type  unions.  Within  a 
separate  region  (territory,  it  is  possible  to  establish 
and efficiently operate a regional innovation project 
(RIP)  with  inclusion  of  all  stages  of  innovation 
formation and implementation (from organization of 
research  work  to  the  specific  innovative  product 
production (Antonioli et al., 2014). It is important to 
ensure a balance of interests of the participants in the 
integration structure and optimize its structure. 
The  assessment  features  of  the  regional 
innovation  sustainability.  Strategies  for  regional 
innovation  development  should  consider  significant 
differences  between  regions  (orientation  towards 
export  or  import,  industry,  agriculture,  tourism) 
(Karayannis and Grigorudis, 2016), it is necessary to 
consider the resources, advantages and potential of a 
particular  region.  The  success  of  innovation 
development  in  any  country  is  determined  by 
innovation activities in individual regions, the ability 
of  individual  territories  to  create  and  promote 
innovations,  organize  and  operate  a  regional 
innovation  system  based  on  mutual  understanding, 
optimization of creative functions, and a combination 
of  economic  interests.  A  feature  of  regional 
innovation  development  in  any  country  is  probably 
the heterogeneity, unevenness of the implementation 
of innovative processes in different regions, implying 
uniform  approaches  to  assessing  innovation 
development, but with the obligatory consideration of 
a  particular  region-specific  features,  a  certain 
territory.  It  is  important  to  develop  and  implement 
measures  to  form  and  support  innovation 
sustainability,  considering  specific  features  of  a 
region: 
  it  is  necessary  to  take  into  account  the  initial 
socio-economic state of the region (the level of 
performance  of  the  regional  economy); 
availability  of  resources  (material,  natural, 
scientific, technical, production); 
  availability  of  resources  (material,  natural, 
scientific, technical, production); 
  feasibility  (combined  in  time  and  space)  of 
various  innovations:  marketing,  production, 
financial, product, organizational); 
  the level of human capital development in the 
region  (education  level,  age  structure, 
employment);