The  process  of  acceleration  of  scientific  and 
technological  development,  which  is  a 
prerequisite  for  the  transition  of  national 
economies to the sixth technological mode as a 
result of the fourth industrial revolution; 
  Artificial intelligence production tools, digital 
technologies,  nano-  and  biotechnologies, 
nanobiotechnologies,  and  other 
microelectronic  components  are  predicted  to 
form  the  technological  basis  of  the  new 
technological paradigm;  
  Government  agencies  in  many  countries  are 
taking  a  proactive  stance  with  regard  to 
stimulating  R&D  in  priority  areas  with 
subsequent  dissemination  of  science  and 
technology achievements at the global market 
scale to ensure sustainable development of the 
economy.  
Meanwhile,  the  national  innovation  system  is 
characterized by dispersion of intellectual resources, 
selective financing of innovation projects, poor R&D 
and technology transfer results, and weak linkages in 
the "science-production-commerce" system. 
As a result, the NIS of the domestic economy has 
a  number  of  significant  inconsistencies  in  the 
construction of the management system. The analysis 
of  publications  on  this  issue  and  our  own  research 
allowed us to substantiate and propose a conceptual 
scheme of formation of the organizational mechanism 
of  functioning  of  the  management  system  of  the 
national  innovation  system.  This  approach  can  be 
used as the basis for the transformation and structural 
construction  of  the  management  system  of  NIS 
infrastructure  of  the  national  economy  with  new 
mechanisms  and  tools  to  generate  innovation, 
technology transfer. 
The  results  of  the  study  of  the  formation  of 
innovation environment in the transition period of the 
sixth  technological  mode  allow  us  to  further 
substantiate  a  number  of  provisions  concerning  the 
transformation of the complex of management tasks 
to enhance innovative development.  
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