# Noninvasive Portal Pressure Estimation Model using Finite Element Analysis

### P. Senthil Kumar, A. K. Thittai, R. Krishna Kumar

#### 2020

#### Abstract

Currently, portal pressure is measured by the standard method known as hepatic venous pressure gradient (HVPG). But it is an invasive procedure; therefore, an alternative noninvasive technique to estimate portal pressure is required to monitor portal hypertension. In this work, a 3D portal vein model is developed to study the acoustic interaction with microbubbles in the portal vein. Ultrasound scattering by ultrasound contrast agent (UCA) is modelled and analyzed using finite element analysis in order to estimate portal pressure. It was found from the analysis that the subharmonic component dropped by 1.5 dB as the portal pressure raised from 0 mmHg to 10 mmHg. Over the same pressure range, the fundamental component reduced by only 0.2 dB. The results suggest that the subharmonic component from the nonlinear response of microbubble is strongly affected by the ambient pressure, and the proposed model may be used to estimate portal pressure noninvasively.

Download#### Paper Citation

#### in Harvard Style

Kumar P., Thittai A. and Krishna Kumar R. (2020). **Noninvasive Portal Pressure Estimation Model using Finite Element Analysis**. In *Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 1: BIODEVICES*; ISBN 978-989-758-398-8, SciTePress, pages 306-311. DOI: 10.5220/0009190903060311

#### in Bibtex Style

@conference{biodevices20,

author={P. Senthil Kumar and A. K. Thittai and R. Krishna Krishna Kumar},

title={Noninvasive Portal Pressure Estimation Model using Finite Element Analysis},

booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 1: BIODEVICES},

year={2020},

pages={306-311},

publisher={SciTePress},

organization={INSTICC},

doi={10.5220/0009190903060311},

isbn={978-989-758-398-8},

}

#### in EndNote Style

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 1: BIODEVICES

TI - Noninvasive Portal Pressure Estimation Model using Finite Element Analysis

SN - 978-989-758-398-8

AU - Kumar P.

AU - Thittai A.

AU - Krishna Kumar R.

PY - 2020

SP - 306

EP - 311

DO - 10.5220/0009190903060311

PB - SciTePress