Conjugation Reaction between Citronellal and L-Tyrosine and Its Antimicrobial Properties against Bacteria and Fungi

Rila Suryani, Nazaruddin Nazaruddin, Kartini Hasballah, Muhammad Diah, Hardi Yusuf, Juniarti, Syaifullah Muhammad, Khairan

2019

Abstract

The study of citronellal with L-tyrosin conjugation for antimicrobial properties has been conducted. The aim of this study to determine the relationship stucture between two compounds citronellal and L-tyrosine on antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans. The conjugation product obtained was yellow-white solid amorphous with the Rf value was 0.84 and the percentage of yield was 71.12%. The FT-IR spectra peak at 3205.69 cm-1 is represented the N-H stretching vibration from L-tyrosine, while the spectra appears at 1460.11 - 1438.90 cm-1 are represented the C=N which derived from imine or immonium from shift base reaction between citronellal and L-tyrosine. The GC-MS analysis showed that the peak 15 observed at RT 10.27 min. be expected a conjugation product with the m/z 316 [M+H]+ ion. The antimicrobial activity were determined by well diffusion method and the results showed that product of conjugation were have no antimicrobail activities at concentration tested

Paper Citation

in Harvard Style

Suryani R., Nazaruddin N., Hasballah K., Diah M., Yusuf H., Juniarti., Muhammad S. and Khairan. (2019). Conjugation Reaction between Citronellal and L-Tyrosine and Its Antimicrobial Properties against Bacteria and Fungi.In Proceedings of the 2nd International Conference of Essential Oils - Volume 1: ICEO, ISBN 978-989-758-456-5, pages 74-79. DOI: 10.5220/0009957000740079

in Bibtex Style

@conference{iceo19,
author={Rila Suryani and Nazaruddin Nazaruddin and Kartini Hasballah and Muhammad Diah and Hardi Yusuf and Juniarti and Syaifullah Muhammad and Khairan},
title={Conjugation Reaction between Citronellal and L-Tyrosine and Its Antimicrobial Properties against Bacteria and Fungi},
booktitle={Proceedings of the 2nd International Conference of Essential Oils - Volume 1: ICEO,},
year={2019},
pages={74-79},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009957000740079},
isbn={978-989-758-456-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference of Essential Oils - Volume 1: ICEO,
TI - Conjugation Reaction between Citronellal and L-Tyrosine and Its Antimicrobial Properties against Bacteria and Fungi
SN - 978-989-758-456-5
AU - Suryani R.
AU - Nazaruddin N.
AU - Hasballah K.
AU - Diah M.
AU - Yusuf H.
AU - Juniarti.
AU - Muhammad S.
AU - Khairan.
PY - 2019
SP - 74
EP - 79
DO - 10.5220/0009957000740079