BIODEVICES BASED ON SHAPE-MEMORY POLYMERS - Current Capabilities and Challenges

Andrés Díaz Lantada, Pilar Lafont Morgado, Héctor Lorenzo-Yustos, Vicente Lorenzo Esteban, Julio Muñoz-García, José Luis Muñoz Sanz, Javier Echavarri Otero, Juan Manuel Munoz-Guijosa



Shape-memory polymers are active materials with thermomechanical coupling and a high capability to recover from high levels of deformation, which, combined with their low cost and density has favoured the appearance of numerous applications, particularly those linked to the Medical Industry. In many cases, these materials are of medical standard, which increases the chances of obtaining biocompatible devices. In the last decade enormous progress has been made on many areas, regarding these materials, such as synthesis, characterization, activation and others, aimed at improving their applicability. However, various spheres of action still remain that require more in depth research to promote the production start-up of various shape-memory polymer-based devices that have had laboratory validation. This work sets out the potential these materials provide for developing biodevices and the main advances achieved. Also shown are various medical devices just being developed, as well current study needs and trends.


  1. Lendlein, A., Kelch, S., 2002. Shape-Memory Polymers. Angewandte Chemie International.
  2. Lendlein, A., Kelch, S., 2005. Shape-Memory Polymers. Encyclopedia of Materials: Science and Technology.
  3. Liu, C., Mather, P., 2007. Review of progress in ShapeMemory Polymers. Journal of Materials Chemistry.
  4. Wache, H., 2003. Development of a polymer stent with shape-memory effect as a drug delivery system. Journal of Materials Science - Materials in Medicine.
  5. Lendlein, A., Kelch, S., 2005. Shape-Memory Polymers as Stimuli-sensitive Implant Materials. Clinical Hemorheology and Microcirculation.
  6. Lendlein, A., Langer, R., 2002. Biodegradable, Elastic Shape-Memory Polymers for Potential Biomedical Applications. Science.
  7. Wilson,T., et al., 2006. Shape-memory Polymer Therapeutic Devices for Stroke. Lawrence Livermore National Laboratory.
  8. Small, W., et al., 2005. Laser-activated Shape-Memory Polymer Intravascular Thrombectomy Device. Optics Express.
  9. Yakacki, C.M. et al., 2007. Unconstrained Recovery of Shape-Memory Polymers Networks for Cardiovascular Applications. Biomaterials.
  10. Yakacki, C.M. et al., 2008. Deformation Limits in ShapeMemory Polymers. Advance Engineering Materials.
  11. Gall, K.; Kreiner, P. et al., 2004. Shape-memory Polymers for MEMS Systems. Journal of Microelechtromechanical Systems.
  12. Díaz Lantada, A., Lafont, P. et al., 2008. Treatment of Mitral Valve Insufficiency by Shape-Memory Polymer Based Active Annuloplasty. Biodevices 2008 - International Conference onBiomedical Electronics and Devices. INSTICC Press.
  13. Lafont, P., Díaz Lantada et al., 2006. Patent Document P200603149: Sistema activo de anuloplastia para tratamiento de la insuficiencia mitral y otras patologías cardiovasculares. Oficina Española de Patentes y Marcas.
  14. Bellin, I., et al., 2006. Polymeric Triple-Shape Materials. Proceedings of the National Academy of Sciences.
  15. Volk, B. et al., 2005. Characterization of Shape-memory Polymers. NASA Langley Research Centre. Texas A&M University.
  16. Tobushi, H. et al., 2008. Shape Recovery and Irrecoverable Strain Control in Polyurethane ShapeMemory Polymer. Science and Technology of Advanced Materials.
  17. Liu, C. and Mather, P., 2002. Thermomechanical Characterization of a Tailored Series of Shapememory Polymers. Journal of Applied Medical Polymers.
  18. Liu, Y. et al., 2003. Thermomechanical Recovery Couplings of Shape-memory Polymers in Flexure. Smart Materials and Structures.
  19. Huang, W. and Lee, C., 2006. Thermomechanical Behaviour of a Polyurethane Shape-memory Polymer Foam. Journal of Intelligent Material Systems and Structures.
  20. Liu, Y. et al., 2006. Thermomechanics of shape-memory polymers: Uniaxial experiments and constitutive modelling. Int. Journal of Plasticity.
  21. Yakacki, C.M. et al., 2007. Unconstrained recovery of shape-memory polymer networks for cardiovascular applications. Biomaterials.
  22. Harrysson, O., et al., 2007, Custom-designed orthopaedic implants evaluated using FEM analysis of patient computed tomography data. BMC Musculoskeletal Disorders.
  23. Paumier, G., et al., 2008. Thermoresponsive PolymerBased Microdevice for Nano-Liquid Chromatography. Biodevices 2008 - Int. Conference on Biomedical Electronics and Devices. INSTICC Press.
  24. Lendlein, A., et al., 2005. Light-induced shape-memory polymers. Nature.
  25. Buckley, P., et al., 2006. Inductively Heated Shapememory Polymer for the Magnetic Actuation of Medical Devices. IEEE Transactions on Biomedical Engineering.
  26. Conti, S., et al., 2007. Modelling and Simulation of Magnetic Shape-Memory Polymer Composites. Journal of Mechanics and Physics of Solids.
  27. Yang, B., et al., 2004. On the effects of moisture in a polyurethane shape-memory polymer. Smart Materials and Structures.
  28. Yakacki, C.M. et al., 2008. Cytoxicity and Thermomechanical Behaviour of Biomedical ShapeMemory Polymer Networks Post-sterilization. Biomedical Materials.
  29. Cabanlit, M., et al., 2007, Polyurethane Shape-Memory Polymers Demonstrate Functional Biocompatibility In Vitro. Macromolecular Bioscience.
  30. Sokolowsky, W., et al., 2007, Medical Applications of Shape-memory Polymers. Biomedical Materials.
  31. Bar-Cohen, Y., 2006. Artificial Muscles using Electroactive Polymers (EAP): Capabilities, Challenges and Potential. SPIE Press.

Paper Citation

in Harvard Style

Díaz Lantada A., Lafont Morgado P., Lorenzo-Yustos H., Lorenzo Esteban V., Muñoz-García J., Luis Muñoz Sanz J., Echavarri Otero J. and Munoz-Guijosa J. (2009). BIODEVICES BASED ON SHAPE-MEMORY POLYMERS - Current Capabilities and Challenges . In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2009) ISBN 978-989-8111- 64-7, pages 137-144. DOI: 10.5220/0001123901370144

in Bibtex Style

author={Andrés Díaz Lantada and Pilar Lafont Morgado and Héctor Lorenzo-Yustos and Vicente Lorenzo Esteban and Julio Muñoz-García and José Luis Muñoz Sanz and Javier Echavarri Otero and Juan Manuel Munoz-Guijosa},
title={BIODEVICES BASED ON SHAPE-MEMORY POLYMERS - Current Capabilities and Challenges},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2009)},
isbn={978-989-8111- 64-7},

in EndNote Style

JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2009)
TI - BIODEVICES BASED ON SHAPE-MEMORY POLYMERS - Current Capabilities and Challenges
SN - 978-989-8111- 64-7
AU - Díaz Lantada A.
AU - Lafont Morgado P.
AU - Lorenzo-Yustos H.
AU - Lorenzo Esteban V.
AU - Muñoz-García J.
AU - Luis Muñoz Sanz J.
AU - Echavarri Otero J.
AU - Munoz-Guijosa J.
PY - 2009
SP - 137
EP - 144
DO - 10.5220/0001123901370144