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Authors: Gennady Denisov ; Tomoko Ohyama ; Tihana Jovanic and Marta Zlatic

Affiliation: Howard Hughes Medical Institute, United States

ISBN: 978-989-8565-36-5

Keyword(s): Animal Behavior, Automated Tracking, High-throughput Detection, Model, Algorithm, Software, Signal Processing, Statistical Analysis, Feature Extraction, Hit Detection.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Signal Processing ; Physiological Processes and Bio-Signal Modeling, Non-Linear Dynamics

Abstract: Analysis of behaviors of model organisms has a number of applications, particularly to determination of the function of genes and neurons. Drosophila larva is an especially convenient model system for this kind of study because of availability of powerful genetic analysis tools and of automated tracking software that allows high-throughput recording of animal’s shape and position characteristics as time-dependent signals. We have developed an open source software that allows a high-throughput detection and analysis of a comprehensive set of meaningful behaviors of this species. Using the recorded signals as input variables and a set of processing thresholds as parameters, the software employs model-based algorithms to detect the behavioral actions with high accuracy, typically 1-5%. For each detected action it extracts and stores meaningful quantitative features that allow statistical discrimination of mutants from wild type animals and set stage for subsequent application of machine learning techniques to classification of the mutants. (More)

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Paper citation in several formats:
Denisov, G.; Ohyama, T.; Jovanic, T. and Zlatic, M. (2013). Model-based Detection and Analysis of Animal Behaviors using Signals Extracted by Automated Tracking.In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2013) ISBN 978-989-8565-36-5, pages 175-181. DOI: 10.5220/0004235101750181

@conference{biosignals13,
author={Gennady Denisov. and Tomoko Ohyama. and Tihana Jovanic. and Marta Zlatic.},
title={Model-based Detection and Analysis of Animal Behaviors using Signals Extracted by Automated Tracking},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2013)},
year={2013},
pages={175-181},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004235101750181},
isbn={978-989-8565-36-5},
}

TY - CONF

JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2013)
TI - Model-based Detection and Analysis of Animal Behaviors using Signals Extracted by Automated Tracking
SN - 978-989-8565-36-5
AU - Denisov, G.
AU - Ohyama, T.
AU - Jovanic, T.
AU - Zlatic, M.
PY - 2013
SP - 175
EP - 181
DO - 10.5220/0004235101750181

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