Authors:
Rudy Agustriyanto
;
Puguh Setyopratomo
and
Akbarningrum Fatmawati
Affiliation:
Faculty of Engineering, The University of Surabaya, Jl. Raya Kalirungkut, Surabaya, Indonesia, Indonesia
Keyword(s):
Bioprocess control, simulation, PID controller, bioreactor
Abstract:
In a continuous bioreactor, feed is added, and the product flow is removed at a constant rate. The objective is to maintain the system at a steady state with high product formation. This can produce a very productive process, with a low operating cost. However, there are operational challenges, especially on an industrial scale, because they require tightly controlled conditions and strong monitoring methods. For long operation, the system suffers a higher risk of contamination. This paper investigated the PID (Proportional integral Derivative) control strategy of a continuous bioreactor. Several tuning methods of PID controller were used for controller parameters determination (i.e., Direct Synthesis, Ziegler-Nichols (Z-N), and Tyreus-Luyben (TLC)). The results of the closed-loop simulation for servo (setpoint tracking) problems are presented in this paper for each method and compared. The results showed that the three method works well qualitatively. However, the process model of t
he system needs to be modified by introducing 5 hrs time delay, which is useful in obtaining cross over frequency and to make PID possible in the Direct Synthesis method
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