loading
Papers Papers/2022 Papers Papers/2022

Research.Publish.Connect.

Paper

Authors: Inês M. Gonçalves 1 ; 2 ; Miguel Madureira 1 ; Inês M. Miranda 3 ; Helmut Schütte 4 ; Ana S. Moita 2 ; 5 ; Graça Minas 3 ; Stefan Gassmann 4 and Rui Lima 1 ; 6

Affiliations: 1 METRICS, University of Minho, Guimarães, Portugal ; 2 IN+, Instituto Superior Téncico, Universidade de Lisboa, Lisboa, Portugal ; 3 Center for MicroElectromechanical Systems (CMEMS-UMinho), University of Minho, Guimarães, Portugal ; 4 Jade University of Applied Science, Wilhelmshaven, Germany ; 5 CINAMIL, Departamento de Ciências Exatas e de Engenharia, Academia Militar, Instituto Universitário Militar, Lisboa, Portugal ; 6 CEFT, Faculty of Engineering of the University of Porto, Porto, Portugal

Keyword(s): Separation Methods, Blood, Microfluidic Biomedical Devices, Micromilling.

Abstract: The diagnostic of several diseases can be performed by analysing the blood plasma of the patient. Despite of the extensive research work, there is still the need to improve the current low-cost fabrication techniques and devices for the separation of the plasma from the blood cells. Microfluidic biomedical devices have great potential for that process. Hence, two microfluidic devices made by micromilling and sealed with or without the solvent bonding technique were tested by means of a blood analogue fluid. A high-speed video microscopy system was used for the visualization and acquisition of the analogue fluid flow. Then, the separation of particles and plasma was evaluated using the software ImageJ. The device manufactured by the micromilling process without bonding showed a significant reduction of the amount of cells between the entrance and the exit of the microchannels. However, further analysis and optimizations of the microfluidic devices will be conducted in future work.

CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 3.230.143.213

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Gonçalves, I.; Madureira, M.; Miranda, I.; Schütte, H.; Moita, A.; Minas, G.; Gassmann, S. and Lima, R. (2022). Separation Microfluidic Devices Fabricated by Different Milling Processes. In Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2022) - BIODEVICES; ISBN 978-989-758-552-4; ISSN 2184-4305, SciTePress, pages 185-190. DOI: 10.5220/0010906500003123

@conference{biodevices22,
author={Inês M. Gon\c{C}alves. and Miguel Madureira. and Inês M. Miranda. and Helmut Schütte. and Ana S. Moita. and Gra\c{C}a Minas. and Stefan Gassmann. and Rui Lima.},
title={Separation Microfluidic Devices Fabricated by Different Milling Processes},
booktitle={Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2022) - BIODEVICES},
year={2022},
pages={185-190},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010906500003123},
isbn={978-989-758-552-4},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2022) - BIODEVICES
TI - Separation Microfluidic Devices Fabricated by Different Milling Processes
SN - 978-989-758-552-4
IS - 2184-4305
AU - Gonçalves, I.
AU - Madureira, M.
AU - Miranda, I.
AU - Schütte, H.
AU - Moita, A.
AU - Minas, G.
AU - Gassmann, S.
AU - Lima, R.
PY - 2022
SP - 185
EP - 190
DO - 10.5220/0010906500003123
PB - SciTePress