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Authors: Marcello Di Giammarco 1 ; 2 ; Antonella Santone 3 ; Mario Cesarelli 4 ; Fabio Martinelli 5 and Francesco Mercaldo 3 ; 1

Affiliations: 1 Institute for Informatics and Telematics (IIT), National Research Council of Italy (CNR), Pisa, Italy ; 2 Department of Information Engineering, University of Pisa, Pisa, Italy ; 3 Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, Campobasso, Italy ; 4 Department of Engineering, University of Sannio, Benevento, Italy ; 5 Institute for High Performance Computing and Networking (ICAR), National Research Council of Italy (CNR), Rende (CS), Italy

Keyword(s): Adversarial Machine Learning, Generative Adversarial Networks, Deep Learning, Retinal Imaging, Robustness, Security.

Abstract: Adversarial machine learning on medical imaging is one of the many applications for which the evaluation of Generative Adversarial Networks in the medical field has demonstrated remarkable interest. This paper proposes a method in which Convolutional neural Networks are trained and tested on the binary classification of real and fake images, generated through generative adversarial networks. In this paper, the considered experiments are on the RGB fundus retina images of the human eye. Results highlight networks with optimal performance, and completely recognize real/fake classification; however, on the other hand, other networks misclassify the images, enhancing security and reliability problems.

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Paper citation in several formats:
Di Giammarco, M., Santone, A., Cesarelli, M., Martinelli, F. and Mercaldo, F. (2025). On the Detection of Retinal Image Synthesis Obtained Through Generative Adversarial Network. In Proceedings of the 18th International Joint Conference on Biomedical Engineering Systems and Technologies - BIOINFORMATICS; ISBN 978-989-758-731-3; ISSN 2184-4305, SciTePress, pages 611-618. DOI: 10.5220/0013228300003911

@conference{bioinformatics25,
author={Marcello {Di Giammarco} and Antonella Santone and Mario Cesarelli and Fabio Martinelli and Francesco Mercaldo},
title={On the Detection of Retinal Image Synthesis Obtained Through Generative Adversarial Network},
booktitle={Proceedings of the 18th International Joint Conference on Biomedical Engineering Systems and Technologies - BIOINFORMATICS},
year={2025},
pages={611-618},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0013228300003911},
isbn={978-989-758-731-3},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the 18th International Joint Conference on Biomedical Engineering Systems and Technologies - BIOINFORMATICS
TI - On the Detection of Retinal Image Synthesis Obtained Through Generative Adversarial Network
SN - 978-989-758-731-3
IS - 2184-4305
AU - Di Giammarco, M.
AU - Santone, A.
AU - Cesarelli, M.
AU - Martinelli, F.
AU - Mercaldo, F.
PY - 2025
SP - 611
EP - 618
DO - 10.5220/0013228300003911
PB - SciTePress