ON THE FUTILITY OF INTERPRETING OVER-REPRESENTATION OF MOTIFS IN GENOMIC SEQUENCES AS FUNCTIONAL SIGNALS

Nikola Stojanovic

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Paper

ON THE FUTILITY OF INTERPRETING OVER-REPRESENTATION OF MOTIFS IN GENOMIC SEQUENCES AS FUNCTIONAL SIGNALS

Topics: Bioinformatics

In Proceedings of the First International Conference on Bio-inspired Systems and Signal Processing - Volume 2: BIOSIGNALS, 464-471, 2008 , Funchal, Madeira, Portugal

Author: Nikola Stojanovic

Affiliation: University of Texas at Arlington, United States

Keyword(s): Transcriptional control signals, DNA motifs, Regulatory modules.

Related Ontology Subjects/Areas/Topics: Bioinformatics ; Biomedical Engineering ; Biomedical Signal Processing

Abstract: Locating signals for the initiation of gene expression in DNA sequences is an important unsolved problem in genetics. Over more than two decades researchers have applied a large variety of sophisticated computational techniques in order to address it, but only with moderate success. In this paper we investigate the reasons for the relatively poor performance of the current models, and outline some possible directions for future work in this field.

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Paper citation in several formats:

Stojanovic, N. (2008). ON THE FUTILITY OF INTERPRETING OVER-REPRESENTATION OF MOTIFS IN GENOMIC SEQUENCES AS FUNCTIONAL SIGNALS. In Proceedings of the First International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2008) - Volume 2: BIOSIGNALS; ISBN 978-989-8111-18-0; ISSN 2184-4305, SciTePress, pages 464-471. DOI: 10.5220/0001061804640471

@conference{biosignals08,
author={Nikola Stojanovic.},
title={ON THE FUTILITY OF INTERPRETING OVER-REPRESENTATION OF MOTIFS IN GENOMIC SEQUENCES AS FUNCTIONAL SIGNALS},
booktitle={Proceedings of the First International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2008) - Volume 2: BIOSIGNALS},
year={2008},
pages={464-471},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001061804640471},
isbn={978-989-8111-18-0},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the First International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2008) - Volume 2: BIOSIGNALS
TI - ON THE FUTILITY OF INTERPRETING OVER-REPRESENTATION OF MOTIFS IN GENOMIC SEQUENCES AS FUNCTIONAL SIGNALS
SN - 978-989-8111-18-0
IS - 2184-4305
AU - Stojanovic, N.
PY - 2008
SP - 464
EP - 471
DO - 10.5220/0001061804640471
PB - SciTePress