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Author: Heru Sasongko

Affiliation: Universitas Sebelas Maret, Indonesia

ISBN: 978-989-758-349-0

Keyword(s): acute toxicity, eel, fish oil, hematology, omega-3

Abstract: Eel (Anguilla bicolor bicolor) is a fish consumed as food and found in Indonesia. The eel oil is known to contain fatty acids like omega-3. The study aims to determine the effect of acute administration of eel oil to hematological parameters in mice. A total of 24 male Swiss Webster mice were divided into four groups. Group I as the control was not administered by eel oil and administered aquadest instead, group II, III, and IV were given 0.09; 0.25 and 0.74 g/ 20 g B.W, respectively, of eel oil. The oil was administered for 14 days. On day 14th, blood sample was taken from orbital sinus. The hematological parameter consisted of the amount of erythrocyte, leukocyte, hemoglobin, hematocrit, lymphocyte, neutrophil and platelet levels were measured. The data were statistically analyzed by one way ANOVA followed by LSD test. The result is acute administration of eel oil at dose 0.74 g/20 g B.W has caused significant change of hematological parameters, except for erythrocytes and platelets level. The conclusion of this study was that at a dose of 0.74 g/20 g B.W eel oil had an effect on blood hematologic changes in mice. (More)

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Paper citation in several formats:
Sasongko, H. (2018). Effect of Acute Administration of Eel (Anguilla bicolor bicolor) Oil to Hematological Parameters in Mice.In Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD, ISBN 978-989-758-349-0, pages 11-14. DOI: 10.5220/0008238500110014

@conference{mich-phd18,
author={Heru Sasongko.},
title={Effect of Acute Administration of Eel (Anguilla bicolor bicolor) Oil to Hematological Parameters in Mice},
booktitle={Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,},
year={2018},
pages={11-14},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008238500110014},
isbn={978-989-758-349-0},
}

TY - CONF

JO - Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,
TI - Effect of Acute Administration of Eel (Anguilla bicolor bicolor) Oil to Hematological Parameters in Mice
SN - 978-989-758-349-0
AU - Sasongko, H.
PY - 2018
SP - 11
EP - 14
DO - 10.5220/0008238500110014

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