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Authors: Ioana R. Ivascu 1 ; Rabah Zeggari 2 ; Christian Pieralli 2 ; Bruno Wacogne 2 and Christophe Roux 3

Affiliations: 1 Applied Sciences Faculty, Bucarest “Politehnica” University, Romania ; 2 Institut FEMTO-ST, UMR CNRS 6174, France ; 3 Service de Génétique Histologie Biologie du Développement et de la Reproduction UMR645 – Interactions Hôte-Greffon et Ingénierie Cellulaire et Génique & IFR 133: IBCT, CHU St. Jacques Université de Franche-Comté, France

ISBN: 978-989-674-017-7

Keyword(s): In Vitro Fertilization, Maturation estimation, Optical microsystems, Refractive index measurement.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Instrumentation ; Biomedical Instruments and Devices ; Biomedical Metrology ; Biomedical Sensors ; Emerging Technologies ; Telecommunications ; Wireless and Mobile Technologies ; Wireless Information Networks and Systems

Abstract: In this paper, we present an optical microsystem used to measure the refractive index of oocytes. The technique relies on oocytes refraction properties and on the optical coupling between optical fibers. A theoretical model of the system is established by means of matrix optics. A numerical fitting allows calculating the refractive index of the oocytes. In a first time we considered the oocytes like homogeneous spheres. In a second time, we considered that the oocytes consist of a shell (the zona pellucida) and a core (the cell). Experimental results showed that the refractive index of the oocytes increases during the maturation process. In this position paper, we also discuss the temporal evolution of the oocytes maturity and we point out that the maturation should not only be estimated visually but in a more continuous manner. The device we propose could be a solution for such non invasive measurements.

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Paper citation in several formats:
R. Ivascu I.; Zeggari R.; Pieralli C.; Wacogne B.; Roux C. and (2010). MEASURING THE REFRACTIVE INDEX OF OOCYTES BY MEANS OF AN OPTICAL MICROSYSTEM - A Non Invasive Technique to Estimate the Evolution of Oocytes Maturity.In Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010) ISBN 978-989-674-017-7, pages 127-132. DOI: 10.5220/0002756201270132

@conference{biodevices10,
author={Ioana {R. Ivascu} and Rabah Zeggari and Christian Pieralli and Bruno Wacogne and Christophe Roux},
title={MEASURING THE REFRACTIVE INDEX OF OOCYTES BY MEANS OF AN OPTICAL MICROSYSTEM - A Non Invasive Technique to Estimate the Evolution of Oocytes Maturity},
booktitle={Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)},
year={2010},
pages={127-132},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002756201270132},
isbn={978-989-674-017-7},
}

TY - CONF

JO - Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)
TI - MEASURING THE REFRACTIVE INDEX OF OOCYTES BY MEANS OF AN OPTICAL MICROSYSTEM - A Non Invasive Technique to Estimate the Evolution of Oocytes Maturity
SN - 978-989-674-017-7
AU - R. Ivascu, I.
AU - Zeggari, R.
AU - Pieralli, C.
AU - Wacogne, B.
AU - Roux, C.
PY - 2010
SP - 127
EP - 132
DO - 10.5220/0002756201270132

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