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Authors: Yulia Chursinova 1 ; Dmitriy Kulikov 1 ; Dmitry Rogatkin 1 ; Irina Raznitsyna 2 ; 1 ; Darya Mosalskaya 1 and Maksim Bobrov 1

Affiliations: 1 Moscow Regional Research and Clinical Institute "MONIKI", Russian Federation ; 2 National Research Nuclear University MEPhI, Russian Federation

Keyword(s): Skin Fibrosis, Inflammation, Fluorescence, Saturation, Non-invasive, Diagnostics, in Vivo.

Abstract: Currently the examination of skin fibrosis is based on subjective non quantitative methods and requires invasive procedures. Optical techniques abled to evaluate different quantitative parameters of ordered tissues can be used to solve these problem. Measurements of endogenous fluorescence intensity, regional tissue oxyhemoglobin saturation, and blood filling volume allowed to define the high endogenous fluorescence intensity of porphyrin in skin fibrosis. Besides that, the decrease in oxygen intake parameters together with the fluorescence intensity increase of collagen was determined. Consequently the optical diagnostic techniques can become an effective method for skin fibrosis evaluation.

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Paper citation in several formats:
Chursinova, Y.; Kulikov, D.; Rogatkin, D.; Raznitsyna, I.; Mosalskaya, D. and Bobrov, M. (2018). Optical Technology for Fibrotic Skin Changes Objectification in Experimental Systemic Scleroderma. In Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - BIODEVICES; ISBN 978-989-758-277-6; ISSN 2184-4305, SciTePress, pages 194-199. DOI: 10.5220/0006633101940199

@conference{biodevices18,
author={Yulia Chursinova. and Dmitriy Kulikov. and Dmitry Rogatkin. and Irina Raznitsyna. and Darya Mosalskaya. and Maksim Bobrov.},
title={Optical Technology for Fibrotic Skin Changes Objectification in Experimental Systemic Scleroderma},
booktitle={Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - BIODEVICES},
year={2018},
pages={194-199},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006633101940199},
isbn={978-989-758-277-6},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - BIODEVICES
TI - Optical Technology for Fibrotic Skin Changes Objectification in Experimental Systemic Scleroderma
SN - 978-989-758-277-6
IS - 2184-4305
AU - Chursinova, Y.
AU - Kulikov, D.
AU - Rogatkin, D.
AU - Raznitsyna, I.
AU - Mosalskaya, D.
AU - Bobrov, M.
PY - 2018
SP - 194
EP - 199
DO - 10.5220/0006633101940199
PB - SciTePress

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