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Authors: Alexander Tsouknidas 1 ; Nikolaos Michailidis 1 ; Kleovoulos Anagnostidis 1 and Antonios Lontos 2

Affiliations: 1 Aristoteles University of Thessaloniki, Greece ; 2 Frederick University, Cyprus

ISBN: 978-989-8425-90-4

Keyword(s): Dual-energy x-ray absorptiometry, Femoral neck, FEM, Fragility fracture risks.

Related Ontology Subjects/Areas/Topics: Agents ; Artificial Intelligence ; Bioinformatics ; Biomedical Engineering ; Enterprise Information Systems ; Information Systems Analysis and Specification ; Methodologies and Technologies ; Model Design and Evaluation ; Operational Research ; Simulation

Abstract: Osteoporosis is a clinically silent bone pathology usually manifesting in the form of fragility bone fractures. Due to the high morbidity of the disease, the association of noninvasive imaging techniques to the implicated risk factors, could serve as a valuable indicator for surgeons. In the present investigations, the evaluation of 30 patients femurs' bone mineral density was performed in vivo by Dual-energy X-ray absorptiometry (DXA), while the strength characteristics of the examined specimens were determined ex-vivo using uniaxial compression experiments. The obtained stress strain curves, reflect the mechanical properties of the femur while facilitating their correlation to the obtained DXA measurements. FEM simulations revealed critical stress values within the femoral neck, indicating which DXA values represent abnormal high fragility fracture risks and thus should be considered for surgical intervention.

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Paper citation in several formats:
Tsouknidas, A.; Michailidis, N.; Anagnostidis, K. and Lontos, A. (2012). DUAL-ENERGY X-RAY ABSORPTIOMETRY AS AN INDICATOR FOR FRAGILITY FRACTURE RISKS OF THE FEMORAL NECK.In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms - Volume 1: BIOINFORMATICS, (BIOSTEC 2012) ISBN 978-989-8425-90-4, pages 96-101. DOI: 10.5220/0003770000960101

@conference{bioinformatics12,
author={Alexander Tsouknidas. and Nikolaos Michailidis. and Kleovoulos Anagnostidis. and Antonios Lontos.},
title={DUAL-ENERGY X-RAY ABSORPTIOMETRY AS AN INDICATOR FOR FRAGILITY FRACTURE RISKS OF THE FEMORAL NECK},
booktitle={Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms - Volume 1: BIOINFORMATICS, (BIOSTEC 2012)},
year={2012},
pages={96-101},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003770000960101},
isbn={978-989-8425-90-4},
}

TY - CONF

JO - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms - Volume 1: BIOINFORMATICS, (BIOSTEC 2012)
TI - DUAL-ENERGY X-RAY ABSORPTIOMETRY AS AN INDICATOR FOR FRAGILITY FRACTURE RISKS OF THE FEMORAL NECK
SN - 978-989-8425-90-4
AU - Tsouknidas, A.
AU - Michailidis, N.
AU - Anagnostidis, K.
AU - Lontos, A.
PY - 2012
SP - 96
EP - 101
DO - 10.5220/0003770000960101

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