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Authors: Rafia Rafique and Tae Park

Affiliation: Department of Chemistry, Chung-Ang University, Seoul 06974, Republic of Korea

ISBN: 978-989-758-398-8

ISSN: 2184-4305

Keyword(s): Upconversion Nanoparticle, Photoluminescence, Cytotoxicity, Live Cell Imaging.

Abstract: Advancements in the synthesis of upconversion nanoparticles (UCNP) can enable a broad range of biomedical applications. Herein, we fabricated NaYF4:Yb3+/Er3+ UCNP and polyacrylic acid conjugated UCNPs (UCNP@PAA). Characterizations of the resulting particles were conducted using electron microscopy and spectroscopy, X-ray diffraction (XRD), and upconversion luminescence (UCL) analysis. We demonstrated that particles were synthesized with good homogeneity, hexagonal phase, and UCL efficiency. The UCNP@PAA maintained their original particle size and luminescence properties, cellular nontoxicity, in vitro bioimaging, and biocompatibility. Based on these results, we suggest that these particles can be applied in drug-delivery systems and as bioimaging agents in the future.

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Paper citation in several formats:
Rafique, R. and Park, Tae Jung (2020). Photoluminescent Imaging for an Effective Cancer Diagnosis using Upconversion Nanoparticles.In Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 2 BIOIMAGING: BIOIMAGING, ISBN 978-989-758-398-8, ISSN 2184-4305, pages 23-27. DOI: 10.5220/0008691800230027

@conference{bioimaging20,
author={Rafia Rafique. and Park, Tae Jung},
title={Photoluminescent Imaging for an Effective Cancer Diagnosis using Upconversion Nanoparticles},
booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 2 BIOIMAGING: BIOIMAGING,},
year={2020},
pages={23-27},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008691800230027},
isbn={978-989-758-398-8},
}

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 2 BIOIMAGING: BIOIMAGING,
TI - Photoluminescent Imaging for an Effective Cancer Diagnosis using Upconversion Nanoparticles
SN - 978-989-758-398-8
AU - Rafique, R.
AU - Park, Tae Jung
PY - 2020
SP - 23
EP - 27
DO - 10.5220/0008691800230027

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