Authors:
Kon Ha
;
Gi-sung Joo
;
Grace Nisola
;
Wook-Jin Chung
;
C. J. Kang
and
Yong-Sang Kim
Affiliation:
Myongji University, Korea, Republic of
Keyword(s):
Capillary electrophoresis, Electrochemical detector, Lab-On-a-Chip, Miniaturization, Endocrine disruptors, PDMS, ITO, bisphenol A (BPA).
Related
Ontology
Subjects/Areas/Topics:
Biomedical Engineering
;
Biomedical Instruments and Devices
;
Biomedical Sensors
Abstract:
Numerous researches have been focused on capillary electrophoresis (CE) and amperometric detection (AD) using a double-T micro-channel configuration. The combination of these two techniques becomes a powerful analytical tool due to enhanced features in terms of sensitivity and selectivity. The developed CE-AD chip is low cost and requires less power consumption. Its high compatibility with micro-fabrication technology has made it popular for analysis of different compounds. However, due to the need to further miniaturize the CE-AD device, a twisted CE micro-channel configuration is fabricated and tested in this study. Furthermore, enhanced analyte separation due to delayed response time can be achieved using a serpentine CE separation micro-channel. Phenolic compounds were used as testing analytes to confirm the results using different types of running buffers. Also, the data gathered from the new micro-channel configuration is compared with the previously gathered results obtained f
rom double-T separation micro-channels.
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