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Authors: Varitis Emmanouil 1 ; Sagris Dimitrios 2 ; David Constantine 2 and Lontos Antonios 3

Affiliations: 1 Aristoteles University of Thessaloniki, Greece ; 2 Technological Education Institute of Serres, Greece ; 3 Frederick University, Cyprus

Keyword(s): Femoral Head, Cancellous Bone Anisotropy, μ-CT.

Related Ontology Subjects/Areas/Topics: Bioinformatics ; Biomedical Engineering ; Image Analysis ; Structural Bioinformatics ; Structural Variations

Abstract: The structural characteristics of bone are described by features of high complexity, defining the directional anisotropy of its mechanical properties. This phenomenon originates in the orientation of collagen fibers and osteons within the cortical tissue and the trabecular morphology of cancellous bone. the purpose of this study was the examination of the geometrical anisotropy of cancellous bone in the femoral head. 28 femoral heads, harvested during hip replacement of 17 women and 11 men, were studied in total. Cylindrical specimens of 11mm in diameter were extracted perpendicular to the fovea capitis femoris and subjected to micro Computed Tomography (μ-CT). a 11mm sphere was isolated from all samples and the cross-sectional area of the sphere was studied for 8 predefined regions, corresponding to planes perpendicular to principal loading directions of the hip joint. Significant topographical variations of trabecular bone structure in different subchondral regions were determined. in the superior region, the trabecular bone strength was the highest, while the inferior region exhibited the lowest bone strength and medial and lateral regions had intermittent magnitudes. No significant difference in anisotropy was found between male and female samples, although the absolute values were greater in males. The obtained results cohere with recent literature data of osteopenetration experiments in these directions. (More)

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Paper citation in several formats:
Emmanouil, V.; Dimitrios, S.; Constantine, D. and Antonios, L. (2013). Directional Variation of Trabecular Bone in the Femoral Head, a μ-CT based Approach. In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2013) - BIOINFORMATICS; ISBN 978-989-8565-35-8; ISSN 2184-4305, SciTePress, pages 237-241. DOI: 10.5220/0004327702370241

@conference{bioinformatics13,
author={Varitis Emmanouil. and Sagris Dimitrios. and David Constantine. and Lontos Antonios.},
title={Directional Variation of Trabecular Bone in the Femoral Head, a μ-CT based Approach},
booktitle={Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2013) - BIOINFORMATICS},
year={2013},
pages={237-241},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004327702370241},
isbn={978-989-8565-35-8},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2013) - BIOINFORMATICS
TI - Directional Variation of Trabecular Bone in the Femoral Head, a μ-CT based Approach
SN - 978-989-8565-35-8
IS - 2184-4305
AU - Emmanouil, V.
AU - Dimitrios, S.
AU - Constantine, D.
AU - Antonios, L.
PY - 2013
SP - 237
EP - 241
DO - 10.5220/0004327702370241
PB - SciTePress