loading
Papers Papers/2022 Papers Papers/2022

Research.Publish.Connect.

Paper

Paper Unlock

Authors: Ratna Mustriana 1 ; Haryono Utomo 2 and Purwo Sri Rejeki 3

Affiliations: 1 Faculty of medicine Universitas Airlangga, Dr. Soetomo General Hospital and Surabaya, Indonesia ; 2 Department of Orthodontic Dentistry, Faculty of Dentistry Universitas Airlangga and Surabaya, Indonesia ; 3 Departement of Physiology, Faculty of Medicine, Universitas Airlangga, Surabaya and Indonesia, Indonesia

Keyword(s): Capsaicin, Gingivomucosal, Periodontal Tissue

Abstract: In the community, a lot of enthusiasts like spicy food consumption. Spicy flavors in foods containing capsaicin cause heat stimulation in the oral cavity, especially periodontal tissue. Capsaicin in rat gingivomucosal tissue (Rattus novergicus) can induce an inflammatory reaction. The purpose of this study was to prove that capsaicin exposure can affect the occurrence of inflammation in periodontal tissue (periodontitis). Thirty-three Rattus males aged 8-12 weeks and weighing between 200-250 gram were divided into three groups, namely control group K, group treatment 1 (P1) with a 10 mg dose of capsaicin gel, and group treatment 2 (P2) with a 20 mg dose of capsaicin gel. The capsaicin gel was applied to the mandibular anterior mucosa, then was subjected to glass ionomer cement (GIC) and left for 14 days. After treatment, the anterior mandible labial mucosa was taken and HE was performed, then the data were analyzed using Kruskal Wallis. The results of histopathological examination (H PA) showed changes in the number of macrophages and neutrophils. In group K, the number of macrophages was (11.36 ± 1.433) and the number of neutrophils was (10.91 ± 0.701); in group P1 the number of macrophages was (13.27 ± 1.679) and the number of neutrophils was (8.45 ± 0.802); and in group P2 the number of macrophages was (16.18 ± 2.136) and the number of neutrophils was (6.18 ± 0.751). At day 14 the inflammation in the periodontal tissue was apparent with macrophage and neutrophil enlargement compared to the control group (p < 0.05). These results prove that there was an effect of capsaicin exposure of chronic inflammation in periodontal (white) rat periodontal tissue (Rattus novergicus). (More)

CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 18.97.14.81

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Mustriana, R. ; Utomo, H. and Sri Rejeki, P. (2018). Association of Topical Capsaicin Exposure Dosage and Its Influence on Macrophages and Neutrophils in Periodontal Tissue. In Proceedings of Surabaya International Physiology Seminar - SIPS; ISBN 978-989-758-340-7; ISSN 2184-3678, SciTePress, pages 383-388. DOI: 10.5220/0007339503830388

@conference{sips18,
author={Ratna Mustriana and Haryono Utomo and Purwo {Sri Rejeki}},
title={Association of Topical Capsaicin Exposure Dosage and Its Influence on Macrophages and Neutrophils in Periodontal Tissue},
booktitle={Proceedings of Surabaya International Physiology Seminar - SIPS},
year={2018},
pages={383-388},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007339503830388},
isbn={978-989-758-340-7},
issn={2184-3678},
}

TY - CONF

JO - Proceedings of Surabaya International Physiology Seminar - SIPS
TI - Association of Topical Capsaicin Exposure Dosage and Its Influence on Macrophages and Neutrophils in Periodontal Tissue
SN - 978-989-758-340-7
IS - 2184-3678
AU - Mustriana, R.
AU - Utomo, H.
AU - Sri Rejeki, P.
PY - 2018
SP - 383
EP - 388
DO - 10.5220/0007339503830388
PB - SciTePress