Authors:  Nuri 1 ; Bambang Prajogo 2 and  Sukardiman 2

Affiliations: 1 Universitas Airlangga and Universitas Jember, Indonesia ; 2 Universitas Airlangga, Indonesia

ISBN: 978-989-758-347-6

Keyword(s): Guazuma ulmifolia leaf, Fractions, Anti-adipogenic, Preadipocytes

Abstract: Objective: This study purposed to investigate the anti-adipogenic activity of the chloroform, ethyl acetate, and residual ethanol fractions of Guazuma ulmifolia leaf extract. Methods: The fractionation of ethanol extract was carried out by solvent-solvent partition using chloroform and ethyl acetate. Inhibition of fractions to the proliferation and differentiation of primary cultures of rat preadipocytes were tested to investigate the anti- adipogenic activity. Results: Separation of ethanol extract yielded three fractions, i.e. fraction of chloroform, fraction of ethyl acetate, and fraction of residual ethanol. The results of anti-proliferation and anti-differentiation activity test showed that the highest activity was demonstrated by ethyl acetate fraction, followed by residual ethanol fraction and chloroform fraction. The highest total flavonoid content was also shown by the fraction of ethyl acetate. Conclusion: The fraction of ethyl acetate showed the highest anti-adipogenic acti vity and the highest total flavonoid content (More)

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Paper citation in several formats:
Nuri.; Prajogo B.; Sukardiman. and (2018). Anti-Adipogenic Activity of Fractions of Guazuma ulmifolia Leaf.In Proceedings of BROMO Conference - Volume 1: BROMO, ISBN 978-989-758-347-6, pages 255-260. DOI: 10.5220/0008360902550260

author={Nuri and Bambang Prajogo and Sukardiman},
title={Anti-Adipogenic Activity of Fractions of Guazuma ulmifolia Leaf},
booktitle={Proceedings of BROMO Conference - Volume 1: BROMO,},


JO - Proceedings of BROMO Conference - Volume 1: BROMO,
TI - Anti-Adipogenic Activity of Fractions of Guazuma ulmifolia Leaf
SN - 978-989-758-347-6
AU - Nuri.
AU - Prajogo, B.
AU - Sukardiman.
PY - 2018
SP - 255
EP - 260
DO - 10.5220/0008360902550260

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