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Authors: Donato Impedovo 1 ; Giuseppe Pirlo 2 ; Donato Barbuzzi 2 ; Alessandro Balestrucci 2 and Sebastiano Impedovo 2

Affiliations: 1 Bari Polytechnic, Italy ; 2 Bari University, Italy

Keyword(s): Neuromuscular Transfer Function, Handwritten Data Analysis, Alzheimer Disease.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Instrumentation ; Biomedical Instruments and Devices ; Computational Physiology (Virtual Organs) ; Computer-Aided Detection and Diagnosis ; Devices ; Emerging Technologies ; Health Monitoring Devices ; Human-Computer Interaction ; Physiological Computing Systems ; Telecommunications ; Wireless and Mobile Technologies ; Wireless Information Networks and Systems

Abstract: Based on neuromuscular transfer function of the handwriting system, in this paper a non invasive pre diagnosis system for Alzheimer disease alert is proposed. It is well known in fact, that writing originates from spike trains produced within the Central Nervous System (CNS) and more specifically, inside the 4-th and the 6-th regions of the Bradman's map and then transmitted through the first and second order axons to the spinal cord to control the muscles involved in the handwriting as the arm, the forearm, the hand and the pen or pencil utilized for the writing. More specifically, in this work is proposed a new method, not invasive, for early diagnosis of degenerative disability, it can be also useful for monitoring activities related to the progression of neuromuscular disease in order to evaluate the changing related also to the efficiency of the therapies used. Benefit can be obtained not only for the medical field but also for the pharmaceutical developments. Specifica lly in the paper, the results of some experiments have been focused by considering a certain number of persons some of which affect by Alzheimer disease. (More)


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Paper citation in several formats:
Impedovo, D.; Pirlo, G.; Barbuzzi, D.; Balestrucci, A. and Impedovo, S. (2014). Handwritten Processing for Pre Diagnosis of Alzheimer Disease. In Proceedings of the International Conference on Biomedical Electronics and Devices - BIODEVICES, (BIOSTEC 2014) ISBN 978-989-758-013-0; ISSN 2184-4305, pages 193-199. DOI: 10.5220/0004900701930199

author={Donato Impedovo. and Giuseppe Pirlo. and Donato Barbuzzi. and Alessandro Balestrucci. and Sebastiano Impedovo.},
title={Handwritten Processing for Pre Diagnosis of Alzheimer Disease},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - BIODEVICES, (BIOSTEC 2014)},


JO - Proceedings of the International Conference on Biomedical Electronics and Devices - BIODEVICES, (BIOSTEC 2014)
TI - Handwritten Processing for Pre Diagnosis of Alzheimer Disease
SN - 978-989-758-013-0
IS - 2184-4305
AU - Impedovo, D.
AU - Pirlo, G.
AU - Barbuzzi, D.
AU - Balestrucci, A.
AU - Impedovo, S.
PY - 2014
SP - 193
EP - 199
DO - 10.5220/0004900701930199