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Authors: J. A. Lipponen 1 ; P. A. Karjalainen 1 ; M. P. Tarvainen 1 ; J. Kemppainen 2 ; H. Mikkola 2 ; T. Kärki 2 and T. Laitinen 3

Affiliations: 1 University of Eastern Finland, Finland ; 2 Turku University Hospital, Finland ; 3 Kuopio University Hospital, Finland

Keyword(s): ECG, Hypoglycemia, QT-time, Principal component regression.

Related Ontology Subjects/Areas/Topics: Applications and Services ; Biomedical Engineering ; Biomedical Signal Processing ; Computer Vision, Visualization and Computer Graphics ; Medical Image Detection, Acquisition, Analysis and Processing

Abstract: Hypoglycemia has been shown to affect ECG. Reported changes are prolongation of QT-interval and increased R/T amplitude ratio. These ECG changes are suggested to be connected to so-called dead in bed syndrome. Continuous analysis of ECG changes and blood glucose values, during insulin induced hypoglycemia is presented. Altogether 22 subjects were analyzed in three different groups; 1) healthy group 2) diabetic patients diagnosed less 5 years ago and 3) chronic diabetics diagnosed over than 5 years ago. The results showed that 20 of 22 subjects’ QT-time was prolonged during hypoglycemia. In addition, in group 3 changes were smaller than in groups 1 and 2.

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Paper citation in several formats:
A. Lipponen, J.; A. Karjalainen, P.; P. Tarvainen, M.; Kemppainen, J.; Mikkola, H.; Kärki, T. and Laitinen, T. (2011). CONTINUOUS ANALYSIS OF REPOLARIZATION CHARACTERISTICS DURING INSULIN INDUCED HYPOGLYCEMIA. In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2011) - BIOSIGNALS; ISBN 978-989-8425-35-5; ISSN 2184-4305, SciTePress, pages 107-111. DOI: 10.5220/0003122201070111

@conference{biosignals11,
author={J. {A. Lipponen}. and P. {A. Karjalainen}. and M. {P. Tarvainen}. and J. Kemppainen. and H. Mikkola. and T. Kärki. and T. Laitinen.},
title={CONTINUOUS ANALYSIS OF REPOLARIZATION CHARACTERISTICS DURING INSULIN INDUCED HYPOGLYCEMIA},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2011) - BIOSIGNALS},
year={2011},
pages={107-111},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003122201070111},
isbn={978-989-8425-35-5},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2011) - BIOSIGNALS
TI - CONTINUOUS ANALYSIS OF REPOLARIZATION CHARACTERISTICS DURING INSULIN INDUCED HYPOGLYCEMIA
SN - 978-989-8425-35-5
IS - 2184-4305
AU - A. Lipponen, J.
AU - A. Karjalainen, P.
AU - P. Tarvainen, M.
AU - Kemppainen, J.
AU - Mikkola, H.
AU - Kärki, T.
AU - Laitinen, T.
PY - 2011
SP - 107
EP - 111
DO - 10.5220/0003122201070111
PB - SciTePress