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AN INTEGRATED PHYSIOLOGICAL MODEL OF THE LUNG MECHANICS AND GAS EXCHANGE USING ELECTRICAL IMPEDANCE TOMOGRAPHY IN THE ANALYSIS OF VENTILATION STRATEGIES IN ARDS PATIENTS

Topics: Medical Image Detection, Acquisition, Analysis and Processing; Medical Signal Acquisition, Analysis and Processing; Physiological Processes and Bio-Signal Modeling, Non-Linear Dynamics

Authors: M. Denaï 1 ; M. Mahfouf 1 ; A. Wang 1 ; D. A. Linkens 1 and G. H. Mills 2

Affiliations: 1 University of Sheffield, United Kingdom ; 2 Northern General Hospital, United Kingdom

ISBN: 978-989-674-018-4

Keyword(s): Electrical Impedance Tomography, EIT, Medical imaging, Lung mechanics, Alveolus model, Pressure-volume curve, Blood gas model, Mechanical ventilation, Dead-space, Shunt.

Related Ontology Subjects/Areas/Topics: Applications and Services ; Biomedical Engineering ; Biomedical Signal Processing ; Computer Vision, Visualization and Computer Graphics ; Medical Image Detection, Acquisition, Analysis and Processing ; Physiological Processes and Bio-Signal Modeling, Non-Linear Dynamics

Abstract: Thoracic Electrical Impedance Tomography (EIT) is a non-invasive technique which attempts to reconstruct a cross-sectional image of the internal spatial distribution of conductivity from electrical measurements made by injecting small alternating currents via an electrode array placed on the surface of the thorax. Because air is highly resistive to electric currents whereas fluids and blood are good conductors, it is possible to detect changes in lungs air content with EIT enabling the assessment of ventilation distribution. This paper presents a physiological model which integrates a previously developed gas exchange model with a model of the lung mechanics. This model is combined with a two-dimensional (2D) finite element mesh of the thorax to simulate EIT image reconstruction in patients with acute Respiratory Distress Syndrome (ARDS) under mechanical ventilation. The model was able to track lung ventilation distribution under various simulated ARDS conditions and ventilator setti ngs. (More)

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Paper citation in several formats:
Denaï M.; Mahfouf M.; Wang A.; A. Linkens D.; H. Mills G. and (2010). AN INTEGRATED PHYSIOLOGICAL MODEL OF THE LUNG MECHANICS AND GAS EXCHANGE USING ELECTRICAL IMPEDANCE TOMOGRAPHY IN THE ANALYSIS OF VENTILATION STRATEGIES IN ARDS PATIENTS.In Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2010) ISBN 978-989-674-018-4, pages 208-213. DOI: 10.5220/0002709502080213

@conference{biosignals10,
author={M. Denaï and M. Mahfouf and A. Wang and D. {A. Linkens} and G. {H. Mills}},
title={AN INTEGRATED PHYSIOLOGICAL MODEL OF THE LUNG MECHANICS AND GAS EXCHANGE USING ELECTRICAL IMPEDANCE TOMOGRAPHY IN THE ANALYSIS OF VENTILATION STRATEGIES IN ARDS PATIENTS},
booktitle={Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2010)},
year={2010},
pages={208-213},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002709502080213},
isbn={978-989-674-018-4},
}

TY - CONF

JO - Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2010)
TI - AN INTEGRATED PHYSIOLOGICAL MODEL OF THE LUNG MECHANICS AND GAS EXCHANGE USING ELECTRICAL IMPEDANCE TOMOGRAPHY IN THE ANALYSIS OF VENTILATION STRATEGIES IN ARDS PATIENTS
SN - 978-989-674-018-4
AU - Denaï, M.
AU - Mahfouf, M.
AU - Wang, A.
AU - A. Linkens, D.
AU - H. Mills, G.
PY - 2010
SP - 208
EP - 213
DO - 10.5220/0002709502080213

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