loading
Documents

Research.Publish.Connect.

Paper

Authors: Inding Gusmayadi and  Priyanto

Affiliation: Universitas Muhammadiyah , Indonesia

ISBN: 978-989-758-349-0

Keyword(s): Red ginger extract, Lozenge

Abstract: Lozenges require the tablet hardness of 7-14 Kgf to be a suitable binder. Gelatine can be used to meet the requirement as it creates granules with bad flow time. PVP produces granules with better flow time but it takes a large quantity to reach the lozenges hardness desired. This study aimed to determine the effect of the concentration ratio of gelatine and PVP as binders on the physical properties of red-ginger extract lozenges. Lozenges made employing the wet granulation method following the ratio of gelatine and PVP of 1:1, 1:2, 1:3, 1:4 and 1:5. The hardness test results of the formula 1 to 5 are 9, 14, 16, 13 and 12 Kgf respectively and the friability test results were 0,4%, 0,7%, 0,2%, 0,3% and 0,6% accordingly. The combination of gelatine and PVP as binders provide a significant difference in the hardness and friability of the tablets.

PDF ImageFull Text

Download
CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 18.206.194.83

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Gusmayadi, I. and Priyanto, . (2018). The Effect of Concentration Ratio of Gelatine and Polyvinylpyrrolidone as Binders on the Physical Properties of Red Ginger (Zingiber officinale Rosc.) Extract Lozenges.In Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD, ISBN 978-989-758-349-0, pages 147-153. DOI: 10.5220/0008240901470153

@conference{mich-phd18,
author={Inding Gusmayadi. and Priyanto.},
title={The Effect of Concentration Ratio of Gelatine and Polyvinylpyrrolidone as Binders on the Physical Properties of Red Ginger (Zingiber officinale Rosc.) Extract Lozenges},
booktitle={Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,},
year={2018},
pages={147-153},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008240901470153},
isbn={978-989-758-349-0},
}

TY - CONF

JO - Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,
TI - The Effect of Concentration Ratio of Gelatine and Polyvinylpyrrolidone as Binders on the Physical Properties of Red Ginger (Zingiber officinale Rosc.) Extract Lozenges
SN - 978-989-758-349-0
AU - Gusmayadi, I.
AU - Priyanto, .
PY - 2018
SP - 147
EP - 153
DO - 10.5220/0008240901470153

Login or register to post comments.

Comments on this Paper: Be the first to review this paper.