loading
Documents

Research.Publish.Connect.

Paper

Authors:  Dwitiyanti ; Ni Putu Ermi Hikmawanti ; Kriana Efendi ; Riana Puspa Dewi and Fernita Afriyani

Affiliation: Universitas Muhammadiyah, Indonesia

ISBN: 978-989-758-349-0

Keyword(s): extract, black cincau, black grass jelly, Mesona palustris Blume, anti-hyperlipidemic

Abstract: In Indonesia, Mesona palustris Blume is known as the black cincau (black grass jelly). This plant has been used for various health condition. This study aims to determine the effectiveness of 70% ethanol extract from black cincau leaves as anti-hyperlipidemic on hyperlipidemic hamsters. The dried leaves were extracted using 70% ethanol by maceration method. Syrian hamsters were divided into 7 groups of 4 hamsters), i.e. normal control group, positive control group (fenofibrate 1.235 mg/Kg body weight), positive control group (atorvastatin 2.4 mg/Kg body weight), negative control group, test groups with 3 dose variations (780, 1560, and 3120 mg/Kg body weight each day). All groups except normal control group were induced with high-fat diet for 28 days. Parameters measured were decreased total blood cholesterol, LDL, triglycerides level, and increased blood HDL level. Treatment was performed for 14 days. The 70% ethanol extract of black cincau with a dose of 3120 mg/Kg body weight was a ble to decrease blood total cholesterol level by 51.49%, blood LDL level by 49.92%, and blood triglyceride level by 45.70%. Extract with the dose is also able to increase blood HDL level by 29.30%. Fenofibrate was able to decrease blood triglyceride level by 50.62% and increase blood HDL level by 34.82%, whereas atorvastatin was able to decrease blood total cholesterol level by 54.34% and blood LDL level by 51.13%. It could be concluded that the 70% ethanol extract from black cincau leaves is effective as an anti-hyperlipidemic agent in hyperlipidemic hamster equivalent to positive control group. (More)

PDF ImageFull Text

Download
CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 3.80.4.76

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Dwitiyanti, .; Hikmawanti, N.; Efendi, K.; Dewi, R. and Afriyani, F. (2018). Anti-Hyperlipidemic Effect of 70% Ethanol Extract from Mesona palustris Blume Leaves on Male Hamsters.In Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD, ISBN 978-989-758-349-0, pages 61-65. DOI: 10.5220/0008239400610065

@conference{mich-phd18,
author={Dwitiyanti. and Ni Putu Ermi Hikmawanti. and Kriana Efendi. and Riana Puspa Dewi. and Fernita Afriyani.},
title={Anti-Hyperlipidemic Effect of 70% Ethanol Extract from Mesona palustris Blume Leaves on Male Hamsters},
booktitle={Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,},
year={2018},
pages={61-65},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008239400610065},
isbn={978-989-758-349-0},
}

TY - CONF

JO - Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,
TI - Anti-Hyperlipidemic Effect of 70% Ethanol Extract from Mesona palustris Blume Leaves on Male Hamsters
SN - 978-989-758-349-0
AU - Dwitiyanti, .
AU - Hikmawanti, N.
AU - Efendi, K.
AU - Dewi, R.
AU - Afriyani, F.
PY - 2018
SP - 61
EP - 65
DO - 10.5220/0008239400610065

Login or register to post comments.

Comments on this Paper: Be the first to review this paper.