loading
Documents

Research.Publish.Connect.

Paper

Authors: Vera Ladeska ; Ani Pahriyani and Monika Silviani Gunawijaya

Affiliation: Universitas Muhammadiyah , Indonesia

ISBN: 978-989-758-349-0

Keyword(s): Uric acid, Anredera cordifolia (Ten.) Steenis, antihyperuricemic, Binahong leaves

Abstract: Hyperuricemia is an abnormally high level of uric acid in a blood. Binahong leaves (Anredera cordifolia (Ten.) Steenis) is one of the plants traditionally used as an antihyperuricemic remedy. This study aims to determine the ethanol 70% subfraction activity of binahong leaves on the uric acid level of male white mice. Antihyperuricemia assay was conducted for 36 days by dividing 24 mice into six groups. There are normal control who was given standard feed and Na CMC 0.5%, positive control was given purine and allopurinol 0.8 mg/20 g BW and the assay group was given a purine feed and binahong leaves subfraction SF 3 with a dose of 1.83 mg/20gBW, 3.60 mg/20gBW, and 5.40 mg/20gBW. Blood sampling was conducted by orbital sinus after 2 hours from induction of potassium oxonate. Blood sampling was measured with an enzymatic method using a clinical spectrophotometer. The result showed that the third dose had no significant difference to the positive control with a percentage of decrease of 5 6.6%. The conclusion is that binahong leaves subfraction has the same activity as an antihyperuricemic agent with allopurinol at dose 5.40 mg/20gBW. (More)

PDF ImageFull Text

Download
CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 3.80.4.76

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Ladeska, V.; Pahriyani, A. and Gunawijaya, M. (2018). The Potency of Binahong Leaves (Anredera cordifolia (Ten.) Steenis) Subfraction with Ethanol 70% as an Antihyperuricemic Agent.In Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD, ISBN 978-989-758-349-0, pages 143-146. DOI: 10.5220/0008240801430146

@conference{mich-phd18,
author={Vera Ladeska. and Ani Pahriyani. and Monika Silviani Gunawijaya.},
title={The Potency of Binahong Leaves (Anredera cordifolia (Ten.) Steenis) Subfraction with Ethanol 70% as an Antihyperuricemic Agent},
booktitle={Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,},
year={2018},
pages={143-146},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008240801430146},
isbn={978-989-758-349-0},
}

TY - CONF

JO - Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,
TI - The Potency of Binahong Leaves (Anredera cordifolia (Ten.) Steenis) Subfraction with Ethanol 70% as an Antihyperuricemic Agent
SN - 978-989-758-349-0
AU - Ladeska, V.
AU - Pahriyani, A.
AU - Gunawijaya, M.
PY - 2018
SP - 143
EP - 146
DO - 10.5220/0008240801430146

Login or register to post comments.

Comments on this Paper: Be the first to review this paper.