loading
Papers Papers/2022 Papers Papers/2022

Research.Publish.Connect.

Paper

Paper Unlock

Authors: Ramona Hodrea 1 ; Sandra Iulianetti 2 ; Clara Ionescu 1 and Robin De Keyser 1

Affiliations: 1 Ghent University, Belgium ; 2 Faculté Polytechnique de Mons, Belgium

Keyword(s): Modeling, Anesthesia, Drug delivery.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Signal Processing ; Physiological Processes and Bio-Signal Modeling, Non-Linear Dynamics

Abstract: This paper presents the development of a MISO (multiple-input single-output) patient model for sedation and analgesia components used in ICU. The two inputs are Propofol and Remifentanil and the output is the Bispectral Index. The MISO model consists of two well-known PK-PD models for Propofol and Remifentanil, and an interaction model which describes the synergistic effect of these two drugs on the Bispectral Index. The interaction model parameters were identified using a nonlinear least squares method. Data collected during clinical trials in ICU at Ghent University Hospital have been used for model development. The final purpose is to use this model for prediction in a model based predictive control strategy.

CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 3.142.199.138

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Hodrea, R.; Iulianetti, S.; Ionescu, C. and De Keyser, R. (2010). MODEL DEVELOPMENT FOR PROPOFOL AND REMIFENTANIL MANAGEMENT DURING ICU ANESTHESIA . In Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2010) - BIOSIGNALS; ISBN 978-989-674-018-4; ISSN 2184-4305, SciTePress, pages 145-150. DOI: 10.5220/0002591101450150

@conference{biosignals10,
author={Ramona Hodrea. and Sandra Iulianetti. and Clara Ionescu. and Robin {De Keyser}.},
title={MODEL DEVELOPMENT FOR PROPOFOL AND REMIFENTANIL MANAGEMENT DURING ICU ANESTHESIA },
booktitle={Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2010) - BIOSIGNALS},
year={2010},
pages={145-150},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002591101450150},
isbn={978-989-674-018-4},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2010) - BIOSIGNALS
TI - MODEL DEVELOPMENT FOR PROPOFOL AND REMIFENTANIL MANAGEMENT DURING ICU ANESTHESIA
SN - 978-989-674-018-4
IS - 2184-4305
AU - Hodrea, R.
AU - Iulianetti, S.
AU - Ionescu, C.
AU - De Keyser, R.
PY - 2010
SP - 145
EP - 150
DO - 10.5220/0002591101450150
PB - SciTePress

- Science and Technology Publications, Lda.
RESOURCES

Proceedings

Papers

Authors

Ontology

CONTACTS

Science and Technology Publications, Lda
Avenida de S. Francisco Xavier, Lote 7 Cv. C,
2900-616 Setúbal, Portugal.

Phone: +351 265 520 185 (National fixed network call)
Fax: +351 265 520 186
Email: info@scitepress.org

EXTERNAL LINKS

PRIMORIS

INSTICC

SCITEVENTS

CROSSREF

PROCEEDINGS SUBMITTED FOR INDEXATION BY:

dblp

Ei Compendex

SCOPUS

Semantic Scholar

Google Scholar

Microsoft Academic