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Authors: Nicoletta Nicolaou and Julius Georgiou

Affiliation: University of Cyprus, Cyprus

Keyword(s): Brain-Computer Interface, EEG, Anaesthesia, Awareness.

Abstract: Intra-operative awareness is experienced when a patient regains consciousness during surgery. This work presents a Brain-Computer Interface system that can be used as part of routine surgery for monitoring the patient state of hypnosis in order to prevent intra-operative awareness. The underlying state of hypnosis is estimated using causality-based features extracted from the spontaneous electrical brain activity (EEG) of the patient and a probabilistic classification framework (Hidden Markov Models). The proposed method is applied to EEG activity from 20 patients under propofol anaesthesia. The mean discrimination performance obtained was 98% and 85% for wakefulness and anaesthesia respectively, with an overall performance accuracy of 92%. The use of a probabilistic framework increases the anaesthetist’s confidence on the estimated state of hypnosis based on the marginal probabilities of the underlying state.

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Paper citation in several formats:
Nicolaou, N. and Georgiou, J. (2013). Monitoring Depth of Hypnosis under Propofol General Anaesthesia - Granger Causality and Hidden Markov Models. In Proceedings of the International Congress on Neurotechnology, Electronics and Informatics (NEUROTECHNIX 2013) - BrainRehab; ISBN 978-989-8565-80-8, SciTePress, pages 256-261. DOI: 10.5220/0004679402560261

@conference{brainrehab13,
author={Nicoletta Nicolaou. and Julius Georgiou.},
title={Monitoring Depth of Hypnosis under Propofol General Anaesthesia - Granger Causality and Hidden Markov Models},
booktitle={Proceedings of the International Congress on Neurotechnology, Electronics and Informatics (NEUROTECHNIX 2013) - BrainRehab},
year={2013},
pages={256-261},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004679402560261},
isbn={978-989-8565-80-8},
}

TY - CONF

JO - Proceedings of the International Congress on Neurotechnology, Electronics and Informatics (NEUROTECHNIX 2013) - BrainRehab
TI - Monitoring Depth of Hypnosis under Propofol General Anaesthesia - Granger Causality and Hidden Markov Models
SN - 978-989-8565-80-8
AU - Nicolaou, N.
AU - Georgiou, J.
PY - 2013
SP - 256
EP - 261
DO - 10.5220/0004679402560261
PB - SciTePress

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