Authors:
Susanne Oertel
1
;
Michael P. M. Jank
1
;
Lothar Frey
1
;
Christian Hofmann
2
;
Nadine Lang
2
and
Matthias Struck
2
Affiliations:
1
Fraunhofer Institute for Integrated Systems and Device Technology IISB, Germany
;
2
Fraunhofer Institute for Integrated Circuits IIS, Germany
Keyword(s):
Screen-printed, Biosensor, Biomedical Sensor, Sweat, Ammonia, Exercise, Ion-selective Electrode, Wearable Device.
Related
Ontology
Subjects/Areas/Topics:
Biomedical Engineering
;
Biomedical Instruments and Devices
;
Biomedical Sensors
;
Devices
;
Health Monitoring Devices
;
Human-Computer Interaction
;
Physiological Computing Systems
Abstract:
The fabrication of fully screen-printed biochemical sensors employing planar integrated solid state electrodes is described. The sensors are developed to fit wearable devices and target the monitoring of ammonia respectively ammonium levels in sweat. Increased ammonium levels in sweat correlate to physical overstrain of muscles, indicated by the breakdown of proteins in muscle cells. The sensor on flexible foil uses an ion-selective working electrode and a reference electrode for potentiometric measurements of the electromotoric force, EMF. For the ammonium ion-selective electrode a cocktail of nonactin was deposited. The printed sensors were calibrated with ammonium standard solutions at a working range between 10-5 M to 0.1 M which corresponds to the range of physiological levels of ammonium in sweat before and during physical strain. The potentiometric characterization of the ion-selective sensor shows a linear behaviour of the EMF versus pC values with a Nernstian slope of 59.3 m
V ± 11.2 mV. The combination of low-cost printed sensors, potentiometric sensing, and the integration with textiles represents a very attractive approach for non-invasive monitoring of individual sports performance to prevent overload during physical training.
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