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Authors: Nicolò Malagutti 1 ; Arvin Dehghani 2 and Rodney A. Kennedy 1

Affiliations: 1 The Australian National University, Australia ; 2 The University of Melbourne, Australia

ISBN: 978-989-8425-89-8

Keyword(s): Drug delivery, Automatic control, Robust control, Adaptive control, Blood pressure, Intensive care, Anaesthesia.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Signal Processing ; Cardiovascular Signals ; Physiological Processes and Bio-Signal Modeling, Non-Linear Dynamics

Abstract: The problem of automatic administration of vasoactive drugs to regulate mean arterial pressure in surgical and postsurgical patients can be considered as a setpoint tracking problem involving a system which is characterised by significant modelling uncertainty in the form of uncertain parameters, unmodelled dynamics and disturbances. Yet, specific levels of performance are required and patient safety must be guaranteed. As part of the development process of a novel Multiple-Model Adaptive Control (MMAC) architecture for this application, we have adopted a mixed-ì synthesis approach to controller design. Simulation results show that the new controllers are capable of improved disturbance rejection and robustness even in the face of large system delays and parametric uncertainty.

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Paper citation in several formats:
Malagutti, N.; Dehghani, A. and A. Kennedy, R. (2012). IMPROVED ROBUST PERFORMANCE IN A SYSTEM FOR AUTOMATIC ADMINISTRATION OF A VASOACTIVE DRUG.In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012) ISBN 978-989-8425-89-8, pages 282-290. DOI: 10.5220/0003794002820290

@conference{biosignals12,
author={Nicolò Malagutti. and Arvin Dehghani. and Rodney A. Kennedy.},
title={IMPROVED ROBUST PERFORMANCE IN A SYSTEM FOR AUTOMATIC ADMINISTRATION OF A VASOACTIVE DRUG},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012)},
year={2012},
pages={282-290},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003794002820290},
isbn={978-989-8425-89-8},
}

TY - CONF

JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012)
TI - IMPROVED ROBUST PERFORMANCE IN A SYSTEM FOR AUTOMATIC ADMINISTRATION OF A VASOACTIVE DRUG
SN - 978-989-8425-89-8
AU - Malagutti, N.
AU - Dehghani, A.
AU - A. Kennedy, R.
PY - 2012
SP - 282
EP - 290
DO - 10.5220/0003794002820290

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