Authors:
Guangyu Zhu
1
;
Masakazu Nakao
2
;
Qi Yuan
3
and
Joon Hock Yeo
4
Affiliations:
1
Xi'an Jiaotong University and Nanyang Technological University, China
;
2
KK Women’s and Children’s Hospital, Singapore
;
3
Xi'an Jiaotong University, China
;
4
Nanyang Technological University, Singapore
Keyword(s):
ePTFE, Artificial Heart Valve, Aortic Valve Replacement.
Related
Ontology
Subjects/Areas/Topics:
Biomaterials
;
Biomechanical Devices
;
Biomedical Engineering
;
Biomedical Instruments and Devices
Abstract:
Truly stentless polymeric valve prosthesis can be a viable alternative for aortic valve replacement (AVR). In the present paper, the dynamic and hemodynamic performance of a novel designed expanded-polytetrafluoroethylene (ePTFE) stentless tri-leaflet valve was assessed experimentally. The in-vitro tests were performed under time-varying physiological pressure by using the Vivitro pulse duplicator. A high-speed camera, a flow meter, and pressure transducers were utilized to evaluate the dynamic leaflet behaviours and coaptation parameters. The maximum effective orifice area, mean pressure gradient, regurgitant volume, leakage volume and energy loss of the stentless ePTFE tri-leaflet valve are 2.86 cm2, 9.89 mmHg, 7.09 ml/beat, 2.81 ml/beat and 129.03 mJ, respectively. The results of the current study may provide a viable option for the future clinical application.