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Authors: Yutaka Ueno 1 ; Masaki Kawata 2 and Shinji Umeyama 1

Affiliations: 1 Neuroscience Research Institute, National Institute of Advanced Industrial Science and Technology, Japan ; 2 Grid Technology Research Center, National Institute of Advanced Industrial Science and Technology, Japan

Abstract: An application of spectral clustering to single particle analysis of a biological molecule is described. Using similarity scores for the given data set, clustering was performed in a factor space made by the eigenvector of the normalized similarity matrix. Image data was thus classified by means of information intrinsic to the ensemble of given data. The method was tested on a simulated transmission electron microscopy image and a real image data set of 70S ribosome. The average images of clusters were obtained by iterative alignment, which successfully represented characteristic views of the target molecules. Comparisons with traditional methods and techniques in practical implementation are discussed.

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Paper citation in several formats:
Ueno, Y.; Kawata, M. and Umeyama, S. (2005). Intrinsic Classification of Single Particle Images by Spectral Clustering. In Proceedings of the 1st International Workshop on Biosignal Processing and Classification (ICINCO 2005) - BPC; ISBN 972-8865-35-X, SciTePress, pages 60-67. DOI: 10.5220/0001193800600067

@conference{bpc05,
author={Yutaka Ueno. and Masaki Kawata. and Shinji Umeyama.},
title={Intrinsic Classification of Single Particle Images by Spectral Clustering},
booktitle={Proceedings of the 1st International Workshop on Biosignal Processing and Classification (ICINCO 2005) - BPC},
year={2005},
pages={60-67},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001193800600067},
isbn={972-8865-35-X},
}

TY - CONF

JO - Proceedings of the 1st International Workshop on Biosignal Processing and Classification (ICINCO 2005) - BPC
TI - Intrinsic Classification of Single Particle Images by Spectral Clustering
SN - 972-8865-35-X
AU - Ueno, Y.
AU - Kawata, M.
AU - Umeyama, S.
PY - 2005
SP - 60
EP - 67
DO - 10.5220/0001193800600067
PB - SciTePress

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