loading
Documents

Research.Publish.Connect.

Paper

Authors: Elly Wardani ;  Dwitiyanti ;  Sediarso and Dwina Puspandiyah

Affiliation: Universitas Muhammadiyah , Indonesia

ISBN: 978-989-758-349-0

Keyword(s): Physalis angulata L., Ceplukan herb extract, Antihyperglycemic, blood glucose

Abstract: Diabetes mellitus is a disease characterized by hyperglycemia as well as progressive changes to the pancreatic beta cell structure. This study was conducted to determine the antihyperglycemic activity of ceplukan herb extract (Physalis angulata L.) in alloxan-induced male Syrian hamsters and high cholesterol feed. The study used 24 hamsters divided into six groups. Group I were given a standard diet and regular drinking water, Group II were given metformin dose 61,66 mg/kg body weight (BW), Group III were alloxan-induced and high cholesterol feed, Groups IV, V and VI were given extract dose 60, 120 and 240 mg/kg BW respectively. The animals were induced alloxan monohydrate as well as were given high cholesterol feed during treatment. Blood sampling was performed on the 29th and 44th day using a clinical spectrophotometer. The results show significant differences between treatment groups (α <0,05), followed by Tukey test. In conclusion, the preparation of herbal extract test ceplukan a t doses of 120 and 240 mg/kg BW could reduce blood glucose levels by 50.84% and 43.41% which is equivalent to metformin dose of 61.66 mg/kg BW with a percentage of 53.12%. (More)

PDF ImageFull Text

Download
CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 34.204.194.190

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Wardani, E.; Dwitiyanti, .; Sediarso, . and Puspandiyah, D. (2018). Antihyperglycemic Activity of Ethanolic Herb Extract of Ceplukan (Physalis angulata L.) in Diabetic Hypercholesterolemia in Male Hamsters.In Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD, ISBN 978-989-758-349-0, pages 133-137. DOI: 10.5220/0008240601330137

@conference{mich-phd18,
author={Elly Wardani. and Dwitiyanti. and Sediarso. and Dwina Puspandiyah.},
title={Antihyperglycemic Activity of Ethanolic Herb Extract of Ceplukan (Physalis angulata L.) in Diabetic Hypercholesterolemia in Male Hamsters},
booktitle={Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,},
year={2018},
pages={133-137},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008240601330137},
isbn={978-989-758-349-0},
}

TY - CONF

JO - Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,
TI - Antihyperglycemic Activity of Ethanolic Herb Extract of Ceplukan (Physalis angulata L.) in Diabetic Hypercholesterolemia in Male Hamsters
SN - 978-989-758-349-0
AU - Wardani, E.
AU - Dwitiyanti, .
AU - Sediarso, .
AU - Puspandiyah, D.
PY - 2018
SP - 133
EP - 137
DO - 10.5220/0008240601330137

Login or register to post comments.

Comments on this Paper: Be the first to review this paper.