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Authors: Radmila Juric 1 ; Eton Williams 1 and Inhwa Kim 2

Affiliations: 1 University of South Eastern Norway, Kongsberg, Norway ; 2 Samsung SDS Europe Ltd, U.K.

Keyword(s): Clinical Trials, Eligibility Criteria, OWL/SWR.

Abstract: Software technologies play an important role in defining clinical trials, their eligibility criteria and recruitment process, in which patient enrol to a trial if they satisfy eligibility criteria. In this research we address the problem of semantic overlapping between eligibility criteria and patient needs through a software architectural model which houses a specific computational model based on reasoning upon the overlapping semantics. The architectural model is deployed using semantic technologies in order to explore the meaning of the relationships between trials, eligibility criteria and patient needs. The novelty is in the reusability and thus converting of the existing conceptual models on deriving eligibility criteria, available in literature, into the proposed OWL model, which can serve any clinical trial and requirements patients may have. This paper is written by computer scientists interested in manipulating semantics of data through computational models using modern sof tware technologies. It serves as an invitation to researchers from the biomedical and translational informatics to debate the future of software support in managing clinical trials. (More)

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Paper citation in several formats:
Juric, R.; Williams, E. and Kim, I. (2020). Semantic Overlapping in Translational Bioinformatics Applied to the Matching between Clinical Trial Eligibility Criteria and Patient Needs. In Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - C2C; ISBN 978-989-758-398-8; ISSN 2184-4305, SciTePress, pages 315-322. DOI: 10.5220/0009406503150322

@conference{c2c20,
author={Radmila Juric. and Eton Williams. and Inhwa Kim.},
title={Semantic Overlapping in Translational Bioinformatics Applied to the Matching between Clinical Trial Eligibility Criteria and Patient Needs},
booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - C2C},
year={2020},
pages={315-322},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009406503150322},
isbn={978-989-758-398-8},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - C2C
TI - Semantic Overlapping in Translational Bioinformatics Applied to the Matching between Clinical Trial Eligibility Criteria and Patient Needs
SN - 978-989-758-398-8
IS - 2184-4305
AU - Juric, R.
AU - Williams, E.
AU - Kim, I.
PY - 2020
SP - 315
EP - 322
DO - 10.5220/0009406503150322
PB - SciTePress