Layer-by-layer Assembled Films for Ocular Drug Delivery

Mónica Araújo; Jorge Morgado; Quirina Ferreira

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Paper

Layer-by-layer Assembled Films for Ocular Drug Delivery

In Proceedings of the 5th International Conference on Photonics, Optics and Laser Technology - Volume 1: BONano, 395-401, 2017 , Porto, Portugal

Authors: Mónica Araújo ¹ ; Jorge Morgado ² and Quirina Ferreira ¹

Affiliations: ¹ Instituto de Telecomunicações, Portugal ; ² Instituto de Telecomunicações and University of Lisbon, Portugal

Keyword(s): Drug Delivery, Layer-by-layer Films, Glaucoma.

Abstract: In this paper we describe a simple and versatile method to prepare drug delivery films composed of an ocular drug used in glaucoma treatment, brimonidine, which was encapsulated in a polymer-beta cyclodextrin. The films were developed in order to allow a controlled sequential release during long periods of time. Here we show that by introducing barrier layers of graphene oxide between the drug delivery ones it is possible to delay the brimonidine release for a few days. The time interval between two dosages of drug release will be controlled by adjusting the number and/or thickness of the graphene layers.

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Paper citation in several formats:

Araújo, M.; Morgado, J. and Ferreira, Q. (2017). Layer-by-layer Assembled Films for Ocular Drug Delivery. In Proceedings of the 5th International Conference on Photonics, Optics and Laser Technology (PHOTOPTICS 2017) - BONano; ISBN 978-989-758-223-3; ISSN 2184-4364, SciTePress, pages 395-401. DOI: 10.5220/0006320503950401

@conference{bonano17,
author={Mónica Araújo. and Jorge Morgado. and Quirina Ferreira.},
title={Layer-by-layer Assembled Films for Ocular Drug Delivery},
booktitle={Proceedings of the 5th International Conference on Photonics, Optics and Laser Technology (PHOTOPTICS 2017) - BONano},
year={2017},
pages={395-401},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006320503950401},
isbn={978-989-758-223-3},
issn={2184-4364},
}

TY - CONF

JO - Proceedings of the 5th International Conference on Photonics, Optics and Laser Technology (PHOTOPTICS 2017) - BONano
TI - Layer-by-layer Assembled Films for Ocular Drug Delivery
SN - 978-989-758-223-3
IS - 2184-4364
AU - Araújo, M.
AU - Morgado, J.
AU - Ferreira, Q.
PY - 2017
SP - 395
EP - 401
DO - 10.5220/0006320503950401
PB - SciTePress