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Authors: Valentina Vassilenko 1 ; Mónica Silva 2 ; Ricardo Alves 2 and João O’Neill 2

Affiliations: 1 NOVA University of Lisbon, NMT and S.A, Portugal ; 2 NOVA University of Lisbon, Portugal

Keyword(s): Diagnostic, Lacrimal Fluid, Ion Mobility Spectrometry, MCC-IMS, Volatile Organic Compounds, VOCs.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Instruments and Devices ; Emerging Technologies ; Telecommunications ; Wireless and Mobile Technologies ; Wireless Information Networks and Systems

Abstract: Analysis of lacrimal fluid is under attention of scientists and physicians as an open “window” for non-invasive assessment to relevant information about the health status. In the present work we propose an innovative method for the analysis of volatile metabolites present in the lacrimal fluid by non-invasive, fast and inexpensive technique: Ion Mobility Spectrometry coupled to a Multi-Capillary Column (MCC-IMS). Experimental protocol for lacrimal fluid collection and its further analysis by MCC-IMS was developed. For the first time this technology was used for the analysis of tears from healthy and diabetic person for a “proof of concept” purpose. Obtained experimental result showed that proposed method is suitable for the sensitive in-situ express analysis of Volatile Organic Compounds (VOCs) from lacrimal fluid and have a promising diagnostic potential.

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Paper citation in several formats:
Vassilenko, V.; Silva, M.; Alves, R. and O’Neill, J. (2013). Instrumental Tools for Express Analysis of Lacrimal Fluids. In Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2013) - BIODEVICES; ISBN 978-989-8565-34-1; ISSN 2184-4305, SciTePress, pages 220-224. DOI: 10.5220/0004329602200224

@conference{biodevices13,
author={Valentina Vassilenko. and Mónica Silva. and Ricardo Alves. and João O’Neill.},
title={Instrumental Tools for Express Analysis of Lacrimal Fluids},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2013) - BIODEVICES},
year={2013},
pages={220-224},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004329602200224},
isbn={978-989-8565-34-1},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2013) - BIODEVICES
TI - Instrumental Tools for Express Analysis of Lacrimal Fluids
SN - 978-989-8565-34-1
IS - 2184-4305
AU - Vassilenko, V.
AU - Silva, M.
AU - Alves, R.
AU - O’Neill, J.
PY - 2013
SP - 220
EP - 224
DO - 10.5220/0004329602200224
PB - SciTePress