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Authors: Maik Hadorn 1 and Peter Eggenberger Hotz 2

Affiliations: 1 University of Zurich, Switzerland ; 2 University of Southern Denmark, Denmark

ISBN: 978-989-674-017-7

Keyword(s): Personalized healthcare, Drug delivery, Encapsulation, Compartmentalization, Vesicle, Liposome.

Related Ontology Subjects/Areas/Topics: Biomaterials ; Biomedical Engineering ; Biomedical Instruments and Devices ; Emerging Technologies ; Nanotechnologies ; Telecommunications ; Wireless and Mobile Technologies ; Wireless Information Networks and Systems

Abstract: Single liposomes and vesicles are successfully utilized as delivery vehicles of pharmaceuticals. However limitations of these unilamellar, single compartments led to the development of encapsulated multicompartment systems that establishes the prospect of multicomponent or multifunctional drug delivery systems. So far compartmentalization is restricted to binary systems. To realize a personalized drug delivery, a programmable linkage of n-entities of different content will be needed. Here we present both a programmable DNA-mediated linkage of three distinct vesicle populations and a novel encapsulation protocol. We discuss how the techniques established in this study might be used in personalized healthcare based on custom-tailored encapsulated multicompartment vesicular drug delivery systems.

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Paper citation in several formats:
Hadorn M.; Eggenberger Hotz P. and (2010). TOWARDS PERSONALIZED DRUG DELIVERY - Preparation of an Encapsulated Multicompartment System.In Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010) ISBN 978-989-674-017-7, pages 5-12. DOI: 10.5220/0002691400050012

@conference{biodevices10,
author={Maik Hadorn and Peter {Eggenberger Hotz}},
title={TOWARDS PERSONALIZED DRUG DELIVERY - Preparation of an Encapsulated Multicompartment System},
booktitle={Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)},
year={2010},
pages={5-12},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002691400050012},
isbn={978-989-674-017-7},
}

TY - CONF

JO - Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)
TI - TOWARDS PERSONALIZED DRUG DELIVERY - Preparation of an Encapsulated Multicompartment System
SN - 978-989-674-017-7
AU - Hadorn, M.
AU - Eggenberger Hotz, P.
PY - 2010
SP - 5
EP - 12
DO - 10.5220/0002691400050012

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