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Authors: Adil Ibrahim and Nicholas K. Taylor

Affiliation: Department of Computer Science, Heriot-Watt University, Edinburgh, U.K.

Keyword(s): Negative Selection, Affinity Function, Distance Measure, BLOSUM, Immune Algorithm, Artificial Immune Systems.

Abstract: This paper presents a novel affinity function for the Negative Selection based algorithm in binary classification. The proposed method and its classification performance are compared to several classifiers using different datasets. One of the binary classification problems includes medical testing to determine if a patient has a particular disease or not. The DBLOSUM in Negative Selection classifier appears to be best suited to classification tasks where false negatives pose a major risk, such as in medical screening and diagnosis. It is more likely than most techniques to result in false positives, but it is as accurate, if not more accurate than most other techniques.

CC BY-NC-ND 4.0

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Paper citation in several formats:
Ibrahim, A. and Taylor, N. (2022). Negative Selection in Classification using DBLOSUM Matrices as Affinity Function. In Proceedings of the 14th International Conference on Agents and Artificial Intelligence - Volume 3: ICAART; ISBN 978-989-758-547-0; ISSN 2184-433X, SciTePress, pages 55-62. DOI: 10.5220/0010771100003116

@conference{icaart22,
author={Adil Ibrahim. and Nicholas K. Taylor.},
title={Negative Selection in Classification using DBLOSUM Matrices as Affinity Function},
booktitle={Proceedings of the 14th International Conference on Agents and Artificial Intelligence - Volume 3: ICAART},
year={2022},
pages={55-62},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010771100003116},
isbn={978-989-758-547-0},
issn={2184-433X},
}

TY - CONF

JO - Proceedings of the 14th International Conference on Agents and Artificial Intelligence - Volume 3: ICAART
TI - Negative Selection in Classification using DBLOSUM Matrices as Affinity Function
SN - 978-989-758-547-0
IS - 2184-433X
AU - Ibrahim, A.
AU - Taylor, N.
PY - 2022
SP - 55
EP - 62
DO - 10.5220/0010771100003116
PB - SciTePress