Authors:
Aleksandra Klimas
1
;
Kamil Gorczewski
2
;
Przemysław Pencak
3
;
Zofia Drzazga
1
and
Uwe Klose
2
Affiliations:
1
University of Silesia, Poland
;
2
University of Tuebingen, Germany
;
3
Mielecki University Hospital of Silesian Medical University, Poland
Keyword(s):
Q-ball Reconstruction, Diffusion Tensor Imaging, Diffusion Phantom, Fibre Crossing.
Related
Ontology
Subjects/Areas/Topics:
Applications and Services
;
Biomedical Engineering
;
Biomedical Signal Processing
;
Computer Vision, Visualization and Computer Graphics
;
Electromagnetic Fields in Biology and Medicine
;
Medical Image Detection, Acquisition, Analysis and Processing
Abstract:
The direction of axons in white matter can be estimated using a deterministic fibre tracking algorithms and diffusion weighted imaging. The aim of this work was to evaluate the data, obtained from pig spines phantom measurements with relatively low b-value, using two types of reconstructions: diffusion tensor imaging (DTI) and q-ball approach. Pigs spines submerged in agar gel were used to prepare a phantom with two crossing populations of fibres. The phantoms were measured in 3T MR scanned for b-value of 1000 and 2000 s/mm2 for q-ball and 200-2000s/mm2 for DTI reconstruction. Analysis of crossing and single fibre population regions in the scanners showed that the median dispersions from the reference directions in case of single fibre population were c.a. 4° and for crossing area c.a. 12° and 6.5° for b-value of 1000 s/mm2 and 2000 s/mm2 respectively. The q-ball approach was able to resolve crossing problem for both low b-values. It was shown here that coherent results can be achiev
ed even with lower b-values than proposed by the theory.
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